Evaluation of Aortic Aneurysms With Focus on Wall Stress and Wall Rupture Risk

NCT ID: NCT02800876

Last Updated: 2016-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2017-12-31

Brief Summary

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Retrospective study to evaluate the impact of computational wall stress analysis based on computed tomography (CT) of ruptured and not-ruptured aortic aneurysms as an additional predictor for rupture with dedicated software.

Detailed Description

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In patients with known aortic aneurysm who received clinically indicated CT during a time period from 01/2004-12/2013 the CT data was evaluated with dedicated software, A4clinics, VASCOPS GmbH, Graz, Austria. The following parameters will be evaluated: exterior and luminal diameter, intraluminal thrombus (ILT) thickness, vessel-, luminal- and intraluminal thrombus volume, peak wall stress (PWS), peak wall rupture risk (PWRR), von Mises-stress and rupture risk-index in the ILT.

Conditions

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Aortic Aneurysm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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asymptomatic not ruptured aneurysm

Patients with asymptomatic not ruptured aortic aneurysms greater than 3 cm who received a clinical indicated CT

CT-acquisition

Intervention Type OTHER

symptomatic not ruptured aneurysm

Patients with symptomatic aortic aneurysms greater than 3 cm who received a clinical indicated CT

CT-acquisition

Intervention Type OTHER

symptomatic ruptured aneurysm

Patients with symptomatic ruptured aortic aneurysms greater than 3 cm who received a clinical indicated CT

CT-acquisition

Intervention Type OTHER

patients with small aneurysms

Patients with small aortic aneurysms approximately 5.5 cm, ruptured and not ruptured, who received a clinical indicated CT

CT-acquisition

Intervention Type OTHER

Interventions

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CT-acquisition

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Clinical indicated CT data from patients with known aortic aneurysms.

Clinical indication was:

* Follow up CT examination by known aortic aneurysm
* Patient with known aortic aneurysm with new acute clinical symptoms
* Patients with clinical suspicion of aortic aneurysm

Exclusion Criteria

* known pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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Thi Dan Linh Nguyen-Kim

Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital Zurich

Zurich, Canton of Zurich, Switzerland

Site Status RECRUITING

Countries

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Switzerland

Facility Contacts

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Thi Dan Linh Nguyen-Kim, Dr. med.

Role: primary

0041442552900

Other Identifiers

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KEK-ZH-Nr. 2015-0156

Identifier Type: -

Identifier Source: org_study_id

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