Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms

NCT ID: NCT06365138

Last Updated: 2024-04-15

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 500 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-01-01
• Study Completion Date: 2030-12-01

Brief Summary

It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.

Detailed Description

The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender, the maximum diameter of the aortic aneurysm and the patient's current smoking status.

However, no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out.

High arterial systolic blood pressure can promote aortic rupture. Blood pressure peaks can occur during physical exertion, for example when lifting heavy loads or during defecation.

Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure. This includes, among other things, the practice of strength training or certain types of sport. This can subsequently lead to a reduction in quality of life, although this cannot currently be substantiated by scientific data. There is also no current guideline recommendation in this regard.

Furthermore, the role of stress and / or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature. There is work on this in connection with aortic dissections, which postulates that an increase in emotional or psychological stress can lead to acute hypertension, which can cause a previously damaged aorta to rupture. A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms.

There are indications that, in addition to gender-specific differences in the occurrence of aortic ruptures, there is also a different risk of rupture based on certain pre-existing conditions, dietary habits and age.

Conditions

Aortic Aneurysm

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: OTHER

Interventions

Bahaviour at the time of an aortic aneurysm rupture

Questionnaire and patient interview, diary for day of rupture and the three previous days

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• inclusion of all patients with ruptured aortic aneurysm in Augsburg University Hospital
• Written consent to participate in the study by the patient or their legal representative

Exclusion Criteria

• Lack of consent

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Epidemiology, Medical Faculty, University Augsburg

UNKNOWN

Sponsor Role: collaborator

University Hospital Augsburg

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Alexander Hyhlik-Duerr, Prof.

Role: STUDY_CHAIR

University Hospital Augsburg Vascular Surgery

Locations

University Hospital Augsburg

Augsburg, , Germany

Site Status: RECRUITING

Countries

Germany

Central Contacts

Tobias Warm, MD

Role: CONTACT

tobias.warm@uk-augsburg.de

+49821400161068

Yvonne Gosslau, MD

Role: CONTACT

yvonne.gosslau@uk-augsburg.de

+49821400161977

Facility Contacts

Tobias Warm, MD

Role: primary

tobias.warm@uk-augsburg.de

+49821400161068

Other Identifiers

Aortic Rupture

Identifier Type: -

Identifier Source: org_study_id