Sex-specific Differences in AAA Complexity

NCT ID: NCT05399706

Last Updated: 2022-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-07-31

Study Completion Date

2024-10-01

Brief Summary

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A retrospective cohort study of computed tomography scans of AAA patients considered for repair, in order to identify sex specific differences in abdominal aortic aneurysm (AAA) metrics and the association between anatomical differences/features of complexity and adverse patient outcome.

Detailed Description

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A retrospective cohort study of computed tomography scans of AAA patients considered for repair.

The study aims to, firstly, identify sex specific differences in abdominal aortic aneurysm (AAA) metrics utilising manual and automated image processing techniques; and secondly, if numbers are sufficient, explore the association between features of AAA complexity and adverse patient outcome.

Conditions

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AAA - Abdominal Aortic Aneurysm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Men

Male participants

CTA Aorta

Intervention Type DIAGNOSTIC_TEST

Computed Tomography Angiography - Aorta Whole

Women

Female Participants

CTA Aorta

Intervention Type DIAGNOSTIC_TEST

Computed Tomography Angiography - Aorta Whole

Interventions

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CTA Aorta

Computed Tomography Angiography - Aorta Whole

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* All adult patients with AAA receiving assessment +/- primary open or endovascular repair at participating centre from 1/1/2010 to 31/12/2020.
* Must have AAA \>= 5cm.
* Must have CT imaging within 1 year of operation or definitive turn down for treatment.

Exclusion Criteria

* Insufficient CT imaging quality (\>3mm slices) or lack of CT within 1 year of operation.
* Insufficient clinical data to establish risk factors or clinical outcomes.
* Ruptured aneurysm, aorto-iliac occlusive disease, isolated iliac aneurysm, penetrating aortic ulcer, dissection, juxta or supra-renal aneurysm.
* Secondary repair/not primary treatment decision for AAA repair.
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Imperial College London

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Imperial College London

London, , United Kingdom

Site Status

Countries

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United Kingdom

Facility Contacts

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Colin Bicknell

Role: primary

+44 20 3312 6072

Anna Louise Pouncey

Role: backup

+44 20 3312 6072

Other Identifiers

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292985

Identifier Type: -

Identifier Source: org_study_id

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