The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

NCT ID: NCT05802706

Last Updated: 2025-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2027-01-01

Brief Summary

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This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

Detailed Description

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The study is a non-randomised, controlled, cross-sectional study of diseased human carotid, femoral and abdominal aortic tissue.

Conditions

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Vascular Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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No intervention.

No intervention.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
* Able to provide informed consent.

Exclusion Criteria

* Patients that are unable to give informed consent.
* Seriously ill/unconscious patients.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital of Limerick

OTHER

Sponsor Role lead

Responsible Party

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Fiona Leahy

CNM II Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital Limerick

Limerick, Limerick, Ireland

Site Status RECRUITING

Countries

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Ireland

Central Contacts

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Fiona Leahy, MSc

Role: CONTACT

061 301111

Facility Contacts

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Fiona Leahy, MSc

Role: primary

061 301111

Other Identifiers

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DVS008

Identifier Type: -

Identifier Source: org_study_id

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