Antithrombotic Strategies in Coronary Artery Dilatations and Aneurysms

NCT ID: NCT07211854

Last Updated: 2025-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

51 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-06

Study Completion Date

2024-09-11

Brief Summary

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Objectives: The discovery of aneurysmal or ectatic lesions of the coronary arteries during coronary angiography or coronary CT angiography poses a triple challenge in terms of aetiology, treatment and prognosis. The aim of this study, based on coronary angiograms performed over a 10-year period at the Centre Hospitalier de Versailles, was to determine which antithrombotic treatment was routinely prescribed to patients with ACC or AEC, the evolution of this long-term treatment, and to analyse the association between the presence/absence of anticoagulant treatment and the rates of ischaemic cardiovascular events and haemorrhagic complications.

Materials and methods: This is a non-interventional, observational, single-centre study conducted at the Versailles Hospital Centre from 2013 to 2023, based on the department's coronary angiography registry. The study included adult patients, living or deceased, hospitalised in the cardiology department who underwent coronary angiography between 1 January 2013 and 31 December 2023, which showed the presence of aneurysms or ectatic atheroma with bi- or tri-vessel coronary involvement.

Detailed Description

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Conditions

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Coronary Artery Dilatations and Aneursyms

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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aneurysmal or ectatic lesions of the coronary arteries

This is a non-interventional, observational, single-centre study conducted at the Centre Hospitalier de Versailles from 2013 to 2023, based on the department's coronary angiography registry. The study included adult patients, both living and deceased, who were hospitalised in the cardiology department and underwent coronary angiography between 1 January 2013 and 31 December 2023, which showed the presence of aneurysms or ectatic atheroma with bi- or tri-vessel coronary involvement.

Anticoagulant Treatment

Intervention Type OTHER

Follow-up of patients with coronary aneurysms and treatments introduced (anticoagulants and/or antiplatelet agents) to monitor the onset of ischaemic or haemorrhagic complications between 2013 and 2023.

Interventions

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Anticoagulant Treatment

Follow-up of patients with coronary aneurysms and treatments introduced (anticoagulants and/or antiplatelet agents) to monitor the onset of ischaemic or haemorrhagic complications between 2013 and 2023.

Intervention Type OTHER

Other Intervention Names

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Antiplatelet therapy

Eligibility Criteria

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Inclusion Criteria

* Patient \> 18 years old
* Patient living or deceased
* Patient with aneurysmal or ectatic coronary artery disease with bi- or tri-truncular involvement at coronary angiography.

Exclusion Criteria

* Patient \< 18 years old
* Monotruncal aneurysmal or ectatic disease
* Absence of coronary aneurysm / ectasia
* Patient's opposition to participation in research
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Franck Assayag

OTHER

Sponsor Role lead

Responsible Party

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Franck Assayag

hospital practitioner

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Franck ASSAYAG

Role: PRINCIPAL_INVESTIGATOR

Versailles Hospital

Locations

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Centre Hospitalier de Versailles

Le Chesnay, , France

Site Status

Countries

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France

Other Identifiers

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2024-A01041-46

Identifier Type: OTHER

Identifier Source: secondary_id

P24/08_ASCADA

Identifier Type: -

Identifier Source: org_study_id

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