The Correlation Between Iodine and Selenium Status in Pregnancy and Risk of Thyroid Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

290 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-12-01

Study Completion Date

2019-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Two hundred and ninety pregnant women with gestational age less than 20 weeks will be recruited in this study. Selenium and iodine conditions, and risk of thyroid disease will be monitored until termination of pregnancy, with pregnancy outcomes recorded.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Longitudinal Study on the Influence of Iodine Nutrition Status on Thyroid Function of Childbearing Age Women During Pregnancy and 6 Weeks Postpartum

NCT05677581

Thyroid Function Iodine Nutrition Status

RECRUITING

Relation Between Maternal Iodine Status and Prenatal Foetal Thyroid Dimension

NCT00162539

Deficiency Disease

COMPLETED NA

Thyroid Function Throughout Pregnancy With and Without Iodine Supplementation

NCT00831402

Pregnancy

COMPLETED NA

Selenium Supplementation in Pregnancy

NCT01465867

Pregnancy Infertility Auto-immune Thyroiditis

COMPLETED NA

Iodine Status in Pregnant Women and Their Newborns: is Congenital Hypothyroidism Related to Iodine Deficiency in Pregnancy?

NCT00505479

Congenital Hypothyroidism Pregnancy Iodine Deficiency

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study will recruit 290 pregnant women with gestational age less than 20 weeks. Iodine and selenium condition will be evaluated through dietary recall (on base of Chinese food ingredient information) and biochemical examinations (serum iodine concentrations, urinary iodine concentrations, serum selenium concentrations, etc). The nutritional status of iodine and selenium will be monitored and followed up for all the included subjects throughout the pregnancy. The information of thyroid function and level of anti-TPO and anti-TG will be collected. And all the complications (especially thyroid disease) in pregnancy will also be recorded. All pregnant women will be followed up until the termination of pregnancy, with pregnancy outcomes recorded.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Iodine Excess in Pregnancy Selenium Excess in Pregnancy Iodine Deficiency in Pregnancy Selenium Deficiency in Pregnancy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Proper selenium and iodine condition

The subjects should have proper dietary intake of selenium and iodine, according to Chinese Dietary Reference Intakes (DRIs) (intake of selenium 65μg/d and iodine 230 μg/d).

The Serum iodine concentration are 45-92μg/L，and the urinary I/Cr 150-249μg/g Cr.

The Serum selenium concentrations are 18-40μg/L.

Not applicable (for observational studies)

Intervention Type OTHER

This study is an observational study. No intervention will be administered for research purposes.

Excessive selenium or iodine condition

The subjects have excessive dietary intake of selenium and iodine, usually more than 2 times of DRIs. The Serum iodine concentration are more than 100μg/L，and the urinary I/Cr more than 300μg/g Cr.

The Serum selenium concentrations are more than 40μg/L.

Not applicable (for observational studies)

Intervention Type OTHER

This study is an observational study. No intervention will be administered for research purposes.

Insufficient selenium or iodine condition

The subjects have insufficient dietary intake of either selenium or iodine, compared with DRIs. The Serum iodine concentration are less than 45μg/L，and the urinary I/Cr less than150μg/g Cr.

The Serum selenium concentrations are less than 18μg/L.