Study on the Effect of Selenium Supplementation on the Structure and Function of Autoimmune Thyroiditis

NCT ID: NCT04942769

Last Updated: 2021-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-12-20

Study Completion Date

2021-10-30

Brief Summary

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To evaluate the effects of exogenous selenium supplementation on autoimmune thyroiditis.

Detailed Description

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In patients with autoimmune thyroiditis, investigators compared changes in thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping values and metabolic indicatorsfrom baseline to the end of treatment (12 weeks)

Conditions

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Selenium

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

patients with Autoimmune thyroiditis
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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selenium

selenium was administered to patients with autoimmune thyroiditis

Group Type EXPERIMENTAL

Selenium

Intervention Type DRUG

selenium 100ug ,take it orally twice daily

Interventions

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Selenium

selenium 100ug ,take it orally twice daily

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Men or women between the ages of 18 and 75
* Clinical diagnosis of autoimmune thyroiditis, serum TPOAb and TGAB positive
* Thyroid function is normal, and no drugs affecting thyroid function such as Umetole and Serge have been used

Exclusion Criteria

* The contraindications indicated in the Chinese instructions of the drug
* Hypothyroidism, hyperthyroidism
* Liver function impairment
* Renal function impairment
* Claustrophobia
* Mental disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Chao Yang Hospital

OTHER

Sponsor Role lead

Responsible Party

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Guang Wang

Professor and Director, Department of Endocrinology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Guang Wang

Role: PRINCIPAL_INVESTIGATOR

Beijing Chao Yang Hospital

Locations

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Beijing Chao-Yang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jia Liu, MD

Role: CONTACT

861085231710

Xiaomeng Sun

Role: CONTACT

861085231711

Facility Contacts

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Jia liu, MD

Role: primary

861085231710

Other Identifiers

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2021-310

Identifier Type: -

Identifier Source: org_study_id

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