Hyperthyroidism: Methimazole Plus L-carnitine and Selenium

NCT ID: NCT04946123

Last Updated: 2025-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-05

Study Completion Date

2025-06-04

Brief Summary

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The study aims to investigate the benefits of methimazole treatment in patients with hyperthyroidism, associated with supplementation of L-carnitine and Selenium.

Detailed Description

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Conditions

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Hyperthyroidism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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methimazole (control)

Patients with hyperthyroidism under methimazole treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

methimazole+L-carnitine+selenium (intervention)

Patients with hyperthyroidism under methimazole treatment + supplementation with L-carnitine and Selenium

Group Type EXPERIMENTAL

L-carnitine+Selenium

Intervention Type DIETARY_SUPPLEMENT

Supplementation with L-carnitine and Selenium

Interventions

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L-carnitine+Selenium

Supplementation with L-carnitine and Selenium

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of hyperthyroidism requiring therapy with methimazole

Exclusion Criteria

* Drug and alcohol abuse;
* Pregnancy;
* Medically uncontrolled psychiatric conditions;
* Interfering therapies (lithium, interferone, TKI, amiodarone)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lo.Li.Pharma s.r.l

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Azienda Ospedaliero-Universitaria Città della scienza e degli studi di Torino

Torino, , Italy

Site Status

Countries

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Italy

Other Identifiers

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L-carnitine Hyperthyroidism

Identifier Type: -

Identifier Source: org_study_id

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