Follow up for Patients With Thyroid Cancer Planed for Radioiodine Scan or Treatment

NCT ID: NCT03624751

Last Updated: 2018-08-10

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 300 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-06-30
• Study Completion Date: 2030-06-30

Brief Summary

The prevalence of thyroid cancer has increased in recent decades. Patients with thyroid cancer need to choose between Thyrogen® injection and Eltroxin® withdrawal before radioiodine therapy or scan. This is a prospective, observational study, aiming to observe the difference of metabolic profiles between patients choose Thyrogen® injection and Eltroxin® withdrawal.

Detailed Description

1. Objective： To observe the difference between Thyogen® injection or Eltroxin® withdrawal on metabolic profile.

2. Background and method:： The prevalence of thyroid cancer has increased in recent decades. Patients with thyroid cancer need to choose between Thyrogen® injection and Eltroxin® withdrawal before radioiodine therapy or scan. This is a prospective, observational study, aiming to observe the difference of metabolic profiles between patients choose Thyrogen® injection and Eltroxin® withdrawal.

Inclusion ： Patient number: 500人

Inclusion criteria :

1. Patients with diagnosis of thyroid cancer。

2. Patients who need radioiodine therapy or scan。

Exclusion criteria:

1. Patients cannot cooperate with blood test.。

2. Patients cannot cooperate with radioiodine therapy。 Study design： Prospective, observational study。

Method： We will collect 20cc blood and 20 cc urine before and after radioiodine therapy during each visit (total 3 visits) and check lipid profiles, glucose profiles and inflammation markers. We will compare the difference between results of patients undergoing Thyrogen® injection and Eltroxin® withdrawal.

Conditions

Thyroid Cancer

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

radioiodine

Patients with thyroid cancer need to choose between Thyrogen® injection and Eltroxin® withdrawal before radioiodine therapy or scan.

Intervention Type: RADIATION

Eligibility Criteria

Inclusion Criteria

1. Patients with diagnosis of thyroid cancer。

2. Patients who need radioiodine therapy or scan。

Exclusion Criteria

1. Patients cannot cooperate with blood test.。

2. Patients cannot cooperate with radioiodine therapy。

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Taichung Veterans General Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Division of Endocrinology and Metabolism in Taichung Veterans General Hospital

Taichung, , Taiwan

Site Status: RECRUITING

Countries

Taiwan

Facility Contacts

I-Te Lee, MD

Role: primary

itlee@vghtc.gov.tw

886-4-23741340

Other Identifiers

CE18104A

Identifier Type: -

Identifier Source: org_study_id