Longitudinal Study on the Influence of Iodine Nutrition Status on Thyroid Function of Childbearing Age Women During Pregnancy and 6 Weeks Postpartum

NCT ID: NCT05677581

Last Updated: 2024-05-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-15

Study Completion Date

2024-12-31

Brief Summary

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The goal of this observational study is to provide a reference for formulating individual appropriate iodine intake programs for women during pregnancy and postpartum and improving the monitoring and evaluation system of maternal iodine nutrition status. The main questions it aims to answer are:

* To analyse the longitudinal changes of urinary iodine, urinary iodine/creatinine ratio, thyroid function and related factors in different periods of early, middle, late pregnancy and 6 weeks postpartum in Beijing area.
* To explore the relationship between iodine nutrition status and the changes of thyroid function and to further clarify the effect of iodine nutrition status on thyroid function of women of childbearing age during pregnancy and postpartum in combination with dietary intake of iodine questionnaire.

Participants will be detected there thyroid function, the level of median urinary iodine and urinary iodine/creatinine.

Researchers will compare healthy women of childbearing age served as the control group in the same period.

Detailed Description

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Conditions

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Thyroid Function Iodine Nutrition Status

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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pregnancy and lactation period women

iodine nutrition status

Intervention Type OTHER

iodine nutrition status

healthy women of childbearing age

iodine nutrition status

Intervention Type OTHER

iodine nutrition status

Interventions

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iodine nutrition status

iodine nutrition status

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* primigravida
* no chronic hypertension, thromboembolic disease, severe gastrointestinal, cardiopulmonary and liver diseases before pregnancy
* no systemic lupus erythematosus, rheumatic diseases and other connective tissue diseases or immune diseases before pregnancy
* no adrenocortical hyperplasia, pituitary endocrine diseases and other diseases before pregnancy


* 20-40 years old
* no chronic hypertension, thromboembolic disease, severe gastrointestinal, cardiopulmonary and liver diseases
* no systemic lupus erythematosus, rheumatic diseases and other connective tissue diseases or immune diseases
* no adrenocortical hyperplasia, pituitary endocrine diseases and other diseases

Exclusion Criteria

* multiple pregnancies and multigravida
* a history of type I or type II diabetes before pregnancy
* a clear history of thyroid diseases before pregnancy
* taking drugs that affect thyroid function and/or blood sugar before or during early pregnancy

Healthy women of childbearing age:


* a history of type I or type II diabetes
* a clear history of thyroid diseases
* taking drugs that affect thyroid function and/or blood sugar
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Beijing Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Beijing Friendship Hospital ,Capital Medical University

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yan Long, Chief Physician/Professor

Role: CONTACT

13671148911

Facility Contacts

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Lei Yang

Role: primary

Other Identifiers

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SF2022-2-2029

Identifier Type: -

Identifier Source: org_study_id

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