The Impact of Non-pulsatile Blood Flow on CO2-Reactivity
NCT ID: NCT03732651
Last Updated: 2018-11-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
32 participants
INTERVENTIONAL
2008-06-11
2013-12-02
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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non-pulsatile blood flow
alteration of PaCO2 level
step changes between 30, 40 and 50 mmHg
pulsatile blood flow
alteration of PaCO2 level
step changes between 30, 40 and 50 mmHg
Interventions
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alteration of PaCO2 level
step changes between 30, 40 and 50 mmHg
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Neurological pathologies
* COPD with CO2 retention
* Women of childbearing age
15 Years
75 Years
ALL
No
Sponsors
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Medical University of Vienna
OTHER
Responsible Party
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Cecilia Veraar
Cecilia Veraar
Locations
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medical University of Vienna
Vienna, , Austria
Countries
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References
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Veraar CM, Rinosl H, Kuhn K, Skhirtladze-Dworschak K, Felli A, Mouhieddine M, Menger J, Pataraia E, Ankersmit HJ, Dworschak M. Non-pulsatile blood flow is associated with enhanced cerebrovascular carbon dioxide reactivity and an attenuated relationship between cerebral blood flow and regional brain oxygenation. Crit Care. 2019 Dec 30;23(1):426. doi: 10.1186/s13054-019-2671-7.
Other Identifiers
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1018730
Identifier Type: -
Identifier Source: org_study_id
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