Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-19

Study Completion Date

2026-04-01

Brief Summary

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Prone Positioning in ARDS: Predicting Neurological Complications via Cerebral Hemodynamics

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Detailed Description

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Collecting Medical Records, Demographic Characteristics, and Clinical Data of Moderate to Severe ARDS Patients Requiring Prone Positioning Treatment at Chengdu Pixdu District People's Hospital, Sichuan Provincial People's Hospital, The Fourth People's Hospital of Chengdu, and Chengdu Shuangliu District First People's Hospital from March 2025 to March 2026.

Conditions

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ARDS (Moderate or Severe)

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Prone ventilation

Cerebral Blood Flow Monitoring Before and After Prone Ventilation in Patients with ARDS.Cerebral blood flow,intracranial pressure,and systemic hemodynamic monitoring were performed at the following time points:before prone positioning(T0),1 hour after prone ventilation(T1),12 hours after prone ventilation(T2),1 hour after returning to the supine position(T3),and 7 days after returning to the supine position(T4).

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age≥18 years
* Meet the diagnostic criteria for ARDS(Acute Respiratory Distress Syndrome),with PaO₂/FiO₂\<150 mmHg,and requiring prone ventilation
* Expected duration of mechanical ventilation\>48 hours
* Written informed consent obtained

Exclusion Criteria

* Presence of contraindications to prone positioning(e.g.,head and neck injuries,spinal instability,severe intracranial hypertension)
* Severe neurological diseases(e.g.,cerebral hemorrhage,cerebral infarction,intracranial space-occupying lesions)that may affect the monitoring of cerebral hemodynamics
* Life-threatening ARDS
* Patients who are unable to undergo neurological assessment
* Poor image quality or absence of images

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No