Artificial Intelligence to Assess the Association Between Facial Characteristics and Coronary Artery Diseases

NCT ID: NCT03731936

Last Updated: 2019-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

6864 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-10

Study Completion Date

2019-08-02

Brief Summary

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The purposes of this study are 1) to explore the association between facial characteristics and the increased risk of coronary artery diseases; 2) to evaluate the diagnostic efficacy of appearance factors for coronary artery diseases.

Detailed Description

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Several age-related appearance factors were described associated with increased risk of coronary artery diseases (CAD). However, several limitations made these facial risk factors hard to be utilized in clinical practice, including 1) low prevalence in CAD patients, 2) lack of specific definition, 3) poor reproducibility in artificial recognition.

Thus, the investigators designed a multi-center, cross-sectional study to explore the association between facial characteristics and CAD and evaluate the diagnostic efficacy of appearance factors for CAD. The investigators will recruit patients undergoing coronary angiography or coronary computer tomography angiography. Patients' baseline information and facial images will be collected. First, the investigators will explore the facial factors associated with CAD by using artificial intelligence technology to compare facial photographs between patients with CAD and without CAD. Secondary, the investigators will evaluate the dose-response relationship between facial characteristics and CAD. Third, the investigators will establish a CAD risk model based on facial factors, and evaluate the diagnostic effect of the model.

Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Model establishment and test group

Patients undergoing coronary angiography or coronary computer tomography angiography will be enrolled. Patients data will be used to establish the facial based diagnostic model of coronary artery diseases, and to prospectively validate the diagnostic effectiveness of the model.

No intervention

Intervention Type OTHER

No intervention

Interventions

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No intervention

No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Undergoing coronary angiography or coronary computer tomography angiography
* Written informed consent

Exclusion Criteria

* Prior percutaneous coronary intervention (PCI)
* Prior coronary artery bypass graft (CABG)
* Screening coronary artery disease before treating other heart diseases
* Without blood biochemistry outcome
* With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
* Other situations which make patients fail to be photographed
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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China National Center for Cardiovascular Diseases

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Beijing Anzhen hospital

Beijing, Beijing Municipality, China

Site Status

Fuwai hospital

Beijing, Beijing Municipality, China

Site Status

Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine

Beijing, Beijing Municipality, China

Site Status

Wuhan union hospital

Wuhan, Hubei, China

Site Status

Xuzhou third people's hospital

Xuzhou, Jiangsu, China

Site Status

The first affiliated hospital of Dalian medical university

Dalian, Liangning, China

Site Status

Shanghai East hospital

Shanghai, Shanghai Municipality, China

Site Status

Shanghai Renji hospital

Shanghai, Shanghai Municipality, China

Site Status

The fisrt affiliated hospital of Wenzhou medical university

Wenzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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20181104-2017-907

Identifier Type: -

Identifier Source: org_study_id

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