Prediction of Coronary Artery Disease Based on Multimodal, Non-contact Information With Artificial Intelligence

NCT ID: NCT06092801

Last Updated: 2025-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2978 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-20

Study Completion Date

2025-04-09

Brief Summary

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The goal of this observational study are 1) to assess the effectiveness of modalities and/or their combination of multimodal non-contact information in predicting coronary artery disease; 2) to prospectively validate the performance of the developed artificial Intelligence models in predicting coronary artery disease.

Detailed Description

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This observational study aims to assess the effectiveness and potential mechanism of modalities of non-contact captured bio-physiological information, including facial RGB information, infrared thermography temperature information, gait information, and wearable device information, individually and/or in combination, in predicting coronary artery disease (CAD) with artificial intelligence technology.

Individuals suspected of CAD and referred for evaluation will be invited to participate in the current study for analyzing the non-contact information and association with underlying CAD status, in order to establish the most efficient artificial Intelligence modeling strategy, and prospectively validate the predictive performance of the developed artificial Intelligence models for CAD prediction.

Conditions

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Coronary Artery Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Individuals suspected of coronary artery disease

Individuals suspected of coronary artery disease and referred for evaluation

No intervention

Intervention Type OTHER

No intervention

Interventions

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No intervention

No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Suspected individuals referred to for coronary angiography or coronary computer tomography angiography.

Exclusion Criteria

* Prior percutaneous coronary intervention (PCI)
* Prior coronary artery bypass graft (CABG)
* Undergoing confirmatory coronary evaluation as pre-operation routines for other cardiac diseases
* With artificial body alteration (e.g. cosmetic surgery, facial trauma, or make-up) that may affect the non-contact information of study interest
* Age less than 18 years old
* Other circumstances that prevent participants from cooperating with the study process
* Decline to consent for study participation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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China National Center for Cardiovascular Diseases

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shen Lin, M.D., Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Chinese Academy of Medical Sciences, Fuwai Hospital

Locations

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Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, Beijing Municipality, China

Site Status

Countries

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China

References

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Lin S, Li Z, Fu B, Chen S, Li X, Wang Y, Wang X, Lv B, Xu B, Song X, Zhang YJ, Cheng X, Huang W, Pu J, Zhang Q, Xia Y, Du B, Ji X, Zheng Z. Feasibility of using deep learning to detect coronary artery disease based on facial photo. Eur Heart J. 2020 Dec 7;41(46):4400-4411. doi: 10.1093/eurheartj/ehaa640.

Reference Type BACKGROUND
PMID: 32818267 (View on PubMed)

Other Identifiers

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2022-GSP-QN-10

Identifier Type: -

Identifier Source: org_study_id

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