AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population
NCT ID: NCT07277686
Last Updated: 2026-01-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1392 participants
OBSERVATIONAL
2025-12-11
2026-08-01
Brief Summary
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1. To verify if the AI algorithm can accurately distinguish between high-risk and low-risk groups by comparing the actual prevalence of CAD in these groups.
2. To compare the CAD detection rate using this AI screening strategy against the natural detection rate in a real-world cohort.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Diagnostic Test Cohort
Participants in this cohort undergo facial image-based AI screening. Subsequently, all participants in this group will undergo Coronary Computed Tomography Angiography (CCTA) as the gold standard reference to verify the diagnosis of CAD. All participants are followed up for 6 months.
No Intervention
No Intervention
Real-world Observational Cohort
Participants in this cohort represent a real-world setting. They are followed up for 6 months to observe the natural detection rate of CAD and the occurrence of MACE outcomes.
No Intervention
No Intervention
Interventions
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No Intervention
No Intervention
Eligibility Criteria
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Inclusion Criteria
* Community high-risk population, defined as individuals meeting at least one of the following criteria:
1. Diagnosed with Diabetes Mellitus;
2. Diagnosed with Hypertension;
3. Advanced age (\> 65 years old).
Exclusion Criteria
* History of diagnosed Heart Failure.
* Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup.
* Refusal to participate in the study.
18 Years
ALL
Yes
Sponsors
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Zhoukou Specialized Disease Hospital
UNKNOWN
Zhoukou Chuanhui District Hospital of Traditional Chinese Medicine
UNKNOWN
Chinese Academy of Medical Sciences, Fuwai Hospital
OTHER
Zhoukou Central Hospital
OTHER
China National Center for Cardiovascular Diseases
OTHER_GOV
Responsible Party
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Locations
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Zhoukou Chuanhui District Hospital of Traditional Chinese Medicine
Zhoukou, Henan, China
Zhoukou Specialized Disease Hospital
Zhoukou, Henan, China
Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2025-ZX165
Identifier Type: -
Identifier Source: org_study_id
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