Evaluation of the Renal Congestion, Perfusion and Function Before and After Diuretic Treatment in the ICU

NCT ID: NCT03704844

Last Updated: 2019-05-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-12-01

Study Completion Date

2021-12-31

Brief Summary

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Renal congestion is a pathological state that can lead to acute kidney failure. Furosemide is known to lower renal congestion by its diuretic effect.

The aim of this trial is to study the reversibility of kidney congestion under diuretic therapy and assess through echodoppler parameters if it can improve renal perfusion and function in congestive ICU patients.

It could in fine lead to a better identification of patients that could benefit from diuretic therapy in the ICU.

Detailed Description

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Conditions

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Renal Congestion

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with renal congestion

non applicable

Intervention Type OTHER

non applicable

Patients without renal congestion

non applicable

Intervention Type OTHER

non applicable

Interventions

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non applicable

non applicable

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patient hospitalized in ICU
* under furosemide treatment

Exclusion Criteria

* participation refusal
* uncontrolled shock (MAP\<65mmHg)
* abdominal compartment syndrome
* diuretic administration in the 6 hours prior to inclusion
* renal replacement therapy or stage 4-5 chronic kidney disease
* atrial fibrillation
* no monitoring of CVP / invasive arterial pressure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens-Picardie

Amiens, , France

Site Status NOT_YET_RECRUITING

CHU de Dijon

Dijon, , France

Site Status NOT_YET_RECRUITING

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Ousama ABOU ARAB

Role: primary

+33 6 22 66 24 84

Pierre Grégoire GUINOT

Role: primary

+33 645871619

Thibaut WIPF

Role: primary

+33 3 69 55 12 64

Other Identifiers

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7148

Identifier Type: -

Identifier Source: org_study_id

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