LUS in Acute Heart Failure Therapeutic Adaptation

NCT ID: NCT04633629

Last Updated: 2020-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

94 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-12-31

Study Completion Date

2021-10-31

Brief Summary

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Evaluate lung ultrasound aspect according to diuretics dosage evolution in patients hospitalized for acute heart failure.

Detailed Description

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EPPICA is an observational and prospective cohort study. The study goal is to evaluate LUS aspect evolution according to diuretics dosage in patients hospitalized for acute heart failure.

Conditions

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Acute Heart Failure Pulmonary Congestion

Keywords

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Lung Ultrasound Diuretics Medical department

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with acute heart failure

Patients hospitalized for acute heart failure in medical department.

Lung ultrasound

Intervention Type OTHER

We will perform daily a lung ultrasound to evaluate pulmonary congestion by counting B-lines.

Interventions

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Lung ultrasound

We will perform daily a lung ultrasound to evaluate pulmonary congestion by counting B-lines.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Acute heart failure diagnosed by a senior physician in the medical department, with a confirmation of a second senior physician.
* Hospitalised in the medical department.
* No objection from the patient of his trusted person.

Exclusion Criteria

* Administrative supervision or deprived of their liberty
* Pulmonary conditions distracting lung ultrasound (pneumonectomy, pulmonary fibrosis)
* Chronically dialysed
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Perrine Dumanoir, Doctor

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Grenoble

Central Contacts

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Perrine Dumanoir, Doctor

Role: CONTACT

Phone: +33476767098

Email: [email protected]

Mélanie Arnaud

Role: CONTACT

Phone: +3376767098

Email: [email protected]

References

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Ohman J, Harjola VP, Karjalainen P, Lassus J. Focused echocardiography and lung ultrasound protocol for guiding treatment in acute heart failure. ESC Heart Fail. 2018 Feb;5(1):120-128. doi: 10.1002/ehf2.12208. Epub 2017 Sep 28.

Reference Type BACKGROUND
PMID: 28960894 (View on PubMed)

Coiro S, Rossignol P, Ambrosio G, Carluccio E, Alunni G, Murrone A, Tritto I, Zannad F, Girerd N. Prognostic value of residual pulmonary congestion at discharge assessed by lung ultrasound imaging in heart failure. Eur J Heart Fail. 2015 Nov;17(11):1172-81. doi: 10.1002/ejhf.344. Epub 2015 Sep 29.

Reference Type BACKGROUND
PMID: 26417699 (View on PubMed)

Gargani L, Pang PS, Frassi F, Miglioranza MH, Dini FL, Landi P, Picano E. Persistent pulmonary congestion before discharge predicts rehospitalization in heart failure: a lung ultrasound study. Cardiovasc Ultrasound. 2015 Sep 4;13:40. doi: 10.1186/s12947-015-0033-4.

Reference Type BACKGROUND
PMID: 26337295 (View on PubMed)

Platz E, Merz AA, Jhund PS, Vazir A, Campbell R, McMurray JJ. Dynamic changes and prognostic value of pulmonary congestion by lung ultrasound in acute and chronic heart failure: a systematic review. Eur J Heart Fail. 2017 Sep;19(9):1154-1163. doi: 10.1002/ejhf.839. Epub 2017 May 30.

Reference Type BACKGROUND
PMID: 28557302 (View on PubMed)

Volpicelli G, Caramello V, Cardinale L, Mussa A, Bar F, Frascisco MF. Bedside ultrasound of the lung for the monitoring of acute decompensated heart failure. Am J Emerg Med. 2008 Jun;26(5):585-91. doi: 10.1016/j.ajem.2007.09.014.

Reference Type BACKGROUND
PMID: 18534289 (View on PubMed)

Rusu DM, Siriopol I, Grigoras I, Blaj M, Ciumanghel AI, Siriopol D, Nistor I, Onofriescu M, Sandu G, Cobzaru B, Scripcariu DV, Diaconu O, Covic AC. Lung Ultrasound Guided Fluid Management Protocol for the Critically Ill Patient: study protocol for a multi-centre randomized controlled trial. Trials. 2019 Apr 25;20(1):236. doi: 10.1186/s13063-019-3345-0.

Reference Type BACKGROUND
PMID: 31023358 (View on PubMed)

Other Identifiers

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2020-A02413-36

Identifier Type: OTHER

Identifier Source: secondary_id

38RC20.328

Identifier Type: -

Identifier Source: org_study_id