Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
7240 participants
INTERVENTIONAL
2017-03-31
2018-11-30
Brief Summary
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The study builds on existing work that has shown very promising results with brain training approaches in older adults. There is good evidence that playing brain training games leads to improvements in brain functions including memory and reasoning. There is also a suggestion that regular involvement in brain training games might help reduce the risk of cognitive decline and dementia later in life. It appears that reasoning, or problem-solving, is particularly important as it is one of the first abilities to decline with age. This study will use this evidence to target reasoning in a specific brain training task. It will also explore the potential role of genetic factors in how people perform in the task.
The study will compare the impact of a Grammatical Reasoning Task (START) with a control task consisting of simple picture-matching. Over 7000 participants will be randomly allocated to either START or the control and will be asked to play the task as often as they wish for a period of six weeks. Both tasks will be delivered entirely online so people will access the study from home on their computers. This will be achieved through our dedicated online research platform, PROTECT, which hosts a cohort of over 20,000 older adults who have provided DNA samples as part of a longitudinal study.
This study will measure the impact of the training on cognition and Instrumental Activities of Daily Living. Assessments will be completed online at baseline, two/six weeks and six months. Overall, this study aims to generate exciting new data about how brain training could be included in guidance on healthy ageing.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Grammatical Reasoning
This group will complete a short-term Intensive Grammatical Reasoning cognitive task delivered online by Wesnes Cognition Ltd (START). Participants will be encouraged to complete the START training once a day for six-weeks.
Grammatical Reasoning
START measures the ability to determine the relationships among different shape combinations which are assigned to grammatical statements about them which can be either correct or incorrect. It is a measure of attention, working memory and executive control.
Control - Card Pairs
The control group will complete a basic picture-matching task that will provide the same level of engagement, but without the learning effects.
Card Pairs
A basic picture-matching task.
Interventions
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Grammatical Reasoning
START measures the ability to determine the relationships among different shape combinations which are assigned to grammatical statements about them which can be either correct or incorrect. It is a measure of attention, working memory and executive control.
Card Pairs
A basic picture-matching task.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Access to a computer with a keyboard and the internet
* Participant registered on the PROTECT study
Exclusion Criteria
50 Years
100 Years
ALL
Yes
Sponsors
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South London and Maudsley NHS Foundation Trust
OTHER
King's College London
OTHER
Wesnes Cognition Ltd
UNKNOWN
University of Exeter
OTHER
Responsible Party
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Principal Investigators
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Anne Corbett, BSc MRes PhD
Role: PRINCIPAL_INVESTIGATOR
University of Exeter Medical School
Locations
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University of Exeter Medical School
Exeter, , United Kingdom
Countries
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Other Identifiers
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216941
Identifier Type: -
Identifier Source: org_study_id
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