Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
18 participants
OBSERVATIONAL
2018-06-29
2020-05-18
Brief Summary
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Detailed Description
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The other samples will be transported to the lab of Dr. Andre van Wijnen (RST) to isolate RNA and protein for mRNA, microRNA and additional protein analysis.
Isolated fibroblasts and ASC's from the lab of Dr. Lott (MCA) will be expanded and passaged 3-5 times. ASCs phenotype will be confirmed by flow cytometry. Cells lines will be duplicated and biobanked at the Mayo Clinic Rochester Biotrust and separately biobanked at the Arizona State University lab of scaffold collaborator, Dr. Stephen Massia. Additional frozen cell lines will transported to the lab of Dr. Andre van Wijnen for further processing. . All cells and materials will be used for testing and to advance the science of regenerative medicine. No biobanked cells or materials from this specific project will be used for any future intervention or treatment in humans.
Conditions
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Study Design
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OTHER
PROSPECTIVE
Study Groups
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Pelvic Organ Prolapse
Patients having vaginal hysterectomy who demonstrate grade III-IV uterovaginal prolapse.
No interventions assigned to this group
Non Pelvic Organ Prolapse
Patients having vaginal hysterectomy who do not demonstrate uterovaginal prolapse.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* at least 18 years old
* Mayo Clinic patient
Exclusion Criteria
18 Years
FEMALE
No
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Johnny Yi
Principal Investigator
Principal Investigators
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Johnny Yi, MD
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic in Arizona
Phoenix, Arizona, United States
Countries
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Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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17-009172
Identifier Type: -
Identifier Source: org_study_id
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