Epidural vs. Wound Catheter Following Liver Resection

NCT ID: NCT03638401

Last Updated: 2018-08-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-03

Study Completion Date

2015-10-05

Brief Summary

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Good postoperative pain control after any major surgery allows early mobilization, minimises postoperative complications and reduces patient distress. Multiple different methods of delivering analgesia have been described.

This study aims to compare postoperative pain control between patients with epidural analgesia versus the combination of continuous infiltration of local anaesthetic with wound catheters, TAP block and IV PCA with opiate analgesia following open liver resection. The investigators expect that pain control will be similar between the two groups but that the utilization of wound catheters will confer benefit due to the lack of systemic side effects associated with epidural analgesia

Detailed Description

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Conditions

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Transplant Surgery

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Study Groups

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Standard treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Intervention arm

Group Type ACTIVE_COMPARATOR

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Intervention Type PROCEDURE

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Interventions

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This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All adult patients scheduled to undergo an open liver resection at this hospital will be eligible to participate.

Exclusion Criteria

* Patients with a contraindication to either epidural or wound catheter
* Inability to give written, informed consent
* Aged less than 18 years old
* Liver resection combined with a secondary surgical procedure
* Body mass index of \<18 or \>40
* Pregnancy or lactation
* A history of chronic pain requiring regular opioid analgesia
* Prisoners
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Leeds Teaching Hospitals NHS Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Leeds Teaching Hospitals NHS Trust

Leeds, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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RL14/11048

Identifier Type: -

Identifier Source: org_study_id

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