A Prospective Comparison of Methadone, Fentanyl, and Morphine for Post-laparotomy Epidural Analgesia
NCT ID: NCT01828840
Last Updated: 2022-03-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
100 participants
INTERVENTIONAL
2014-04-30
2016-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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morphine, epidural
Epidurally administrated morphine
epidural morphine via PCEA
fentanyl, epidural
epidurally administrated fentanyl
epidural fentanyl via PCEA
methadone, epidural
epidurally administrated methadone
epidural methadone via PCEA
morphine, intervenous
intravenously administrated morphine
intravenous morphine via PCA
Interventions
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epidural morphine via PCEA
epidural fentanyl via PCEA
epidural methadone via PCEA
intravenous morphine via PCA
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Illicit drug abusers
* Chronic use of pain medication
* Inability to understand consent form
* Age \< 18
* Renal failure (Clcr\<50 ml/min)
* Chronic use of drugs that can alter plasma levels and\\or effect of the study drugs
* Corrected Q-T interval(QTc)=450msc and above
* Contra-indication for epidural catheter insertion
* Pregnancy
18 Years
99 Years
ALL
No
Sponsors
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Hadassah Medical Organization
OTHER
Responsible Party
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Locations
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Hadassah Medical Organization
Jerusalem, , Israel
Countries
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Other Identifiers
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0080-10-HMO
Identifier Type: -
Identifier Source: org_study_id
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