Safety and Efficacy of the LMA Supreme When Inserted With Patients in the Prone Position

NCT ID: NCT03633942

Last Updated: 2018-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-27

Study Completion Date

2020-07-27

Brief Summary

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This study is a non-randomized, observational, non-comparative prospective study to evaluate the safety, efficacy and performance of the LMA Supreme laryngeal mask airway when used according to the device's Instructions for Use.

Detailed Description

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This study is a non-randomized, observational, non-comparative prospective study to evaluate the safety, efficacy and performance of the LMA Supreme laryngeal mask airway when used according to the device's Instructions for Use. During surgery, standard treatment will be applied, complemented with the recording of study parameters related to safety, efficacy and performance of the LMA Supreme laryngeal mask airway.

Conditions

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Airway Obstruction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational: LMA Supreme

An appropriately sized LMA Supreme will be prepared by removing all air from the cuff while applying manual pressure. A water soluble non-local anesthetic containing lubricant gel will be applied to the fully deflated airway before insertion. A 1 cm column of the gel will be preloaded into the gastric port of the LMA Supreme for the Gel Test.

The cuff will be inflated with a manometer to a pressure of approximately 30cm H2O. If a significant leak is detected, the cuff will be inflated in increments of 5cm H2O until a satisfactory seal is obtained. The final cuff pressure will be recorded. The lungs will then be gently inflated by applying manual pressure to the anesthesia circuit bag while observing the gel column in the LMA Supreme gastric port for movement.

LMA Supreme

Intervention Type DEVICE

Placement of the LMA Supreme supraglottic airway device for patients undergoing outpatient spine surgery in the prone position.

Interventions

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LMA Supreme

Placement of the LMA Supreme supraglottic airway device for patients undergoing outpatient spine surgery in the prone position.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* 18 to 70 years of age
* American Society of Anesthesiology Classification (ASA) I-III patients
* Fasting for 8 hours
* Scheduled surgery with indication for laryngeal mask airway

* Inability to comply with study requirements including follow-up

Exclusion Criteria

* Have contraindicating conditions
* Have had radiotherapy to the neck involving the hypopharynx (risk of trauma, failure to seal effectively).
* Have inadequate mouth opening to permit insertion
* History of hiatal hernia
* Scheduled for minimally invasive spine stabilization procedures such as Transforaminal Lumbar Interbody Fusion (TLIF), Anterior Cervical Discectomy and Fusion (ACDF) (all have neuromonitoring/general endotracheal intubation)
* Scheduled for Joimax procedure (initial anesthetic is MAC)
* Unable to safely position themselves prone with assistance
* History of previous failed LMA Supreme placement
* BMI greater than or equal to 53
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Teleflex

INDUSTRY

Sponsor Role collaborator

Laser Spine Institute

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thor Van Diver, MD

Role: PRINCIPAL_INVESTIGATOR

Laser Spine Institute

George Lin, MD

Role: PRINCIPAL_INVESTIGATOR

Laser Spine Institute

Locations

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Laser Spine Institute

Tampa, Florida, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Catrina Montgomery

Role: CONTACT

813-392-7435

Sean Perry

Role: CONTACT

Facility Contacts

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Catrina Montgomery

Role: primary

813-392-7435

Sean Perry

Role: backup

References

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Smith I, White PF. Use of the laryngeal mask airway as an alternative to a face mask during outpatient arthroscopy. Anesthesiology. 1992 Nov;77(5):850-5. doi: 10.1097/00000542-199211000-00003.

Reference Type BACKGROUND
PMID: 1443736 (View on PubMed)

Brimacombe J. The advantages of the LMA over the tracheal tube or facemask: a meta-analysis. Can J Anaesth. 1995 Nov;42(11):1017-23. doi: 10.1007/BF03011075.

Reference Type BACKGROUND
PMID: 8590490 (View on PubMed)

Brimacombe JR, Berry A. The incidence of aspiration associated with the laryngeal mask airway: a meta-analysis of published literature. J Clin Anesth. 1995 Jun;7(4):297-305. doi: 10.1016/0952-8180(95)00026-e.

Reference Type BACKGROUND
PMID: 7546756 (View on PubMed)

Joshi GP, Inagaki Y, White PF, Taylor-Kennedy L, Wat LI, Gevirtz C, McCraney JM, McCulloch DA. Use of the laryngeal mask airway as an alternative to the tracheal tube during ambulatory anesthesia. Anesth Analg. 1997 Sep;85(3):573-7. doi: 10.1097/00000539-199709000-00016.

Reference Type BACKGROUND
PMID: 9296411 (View on PubMed)

Koga K, Asai T, Vaughan RS, Latto IP. Respiratory complications associated with tracheal extubation. Timing of tracheal extubation and use of the laryngeal mask during emergence from anaesthesia. Anaesthesia. 1998 Jun;53(6):540-4. doi: 10.1046/j.1365-2044.1998.00397.x.

Reference Type BACKGROUND
PMID: 9709138 (View on PubMed)

Hohlrieder M, Brimacombe J, Eschertzhuber S, Ulmer H, Keller C. A study of airway management using the ProSeal LMA laryngeal mask airway compared with the tracheal tube on postoperative analgesia requirements following gynaecological laparoscopic surgery. Anaesthesia. 2007 Sep;62(9):913-8. doi: 10.1111/j.1365-2044.2007.05142.x.

Reference Type BACKGROUND
PMID: 17697218 (View on PubMed)

van Zundert A, Brimacombe J. The LMA Supreme--a pilot study. Anaesthesia. 2008 Feb;63(2):209-10. doi: 10.1111/j.1365-2044.2007.05421.x. No abstract available.

Reference Type BACKGROUND
PMID: 18211462 (View on PubMed)

Verghese C, Ramaswamy B. LMA-Supreme--a new single-use LMA with gastric access: a report on its clinical efficacy. Br J Anaesth. 2008 Sep;101(3):405-10. doi: 10.1093/bja/aen174. Epub 2008 Jun 17.

Reference Type BACKGROUND
PMID: 18559351 (View on PubMed)

Truhlar A, Ferson DZ. Use of the Laryngeal Mask Airway Supreme in pre-hospital difficult airway management. Resuscitation. 2008 Aug;78(2):107-8. doi: 10.1016/j.resuscitation.2008.03.008. Epub 2008 May 27. No abstract available.

Reference Type BACKGROUND
PMID: 18508181 (View on PubMed)

Edgcombe H, Carter K, Yarrow S. Anaesthesia in the prone position. Br J Anaesth. 2008 Feb;100(2):165-83. doi: 10.1093/bja/aem380.

Reference Type BACKGROUND
PMID: 18211991 (View on PubMed)

Sharma V, Verghese C, McKenna PJ. Prospective audit on the use of the LMA-Supreme for airway management of adult patients undergoing elective orthopaedic surgery in prone position. Br J Anaesth. 2010 Aug;105(2):228-32. doi: 10.1093/bja/aeq118. Epub 2010 Jun 10.

Reference Type BACKGROUND
PMID: 20542887 (View on PubMed)

[The Helsinki Declaration of the World Medical Association (WMA). Ethical principles of medical research involving human subjects]. Pol Merkur Lekarski. 2014 May;36(215):298-301. No abstract available. Polish.

Reference Type BACKGROUND
PMID: 24964504 (View on PubMed)

Other Identifiers

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LMA 200

Identifier Type: -

Identifier Source: org_study_id

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