Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.

NCT ID: NCT03630926

Last Updated: 2019-04-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-16

Study Completion Date

2019-12-31

Brief Summary

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This is a double-blind, study to evaluate the performance of NV-VPAC1 PCa Urine Diagnostic Test in three distinct populations being treated at the Intermountain Urology Clinic. The first population (positive control) is comprised of men with biopsy-confirmed PCa who are scheduled for prostatectomy. The second population (negative control) is comprised of men with benign prostatic hypertrophy (BPH) who are scheduled for transurethral resection of the prostate (TURP). The third population (negative control) is comprised of men or women with bladder/kidney stones who are scheduled for a cystoscopy.

Detailed Description

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Conditions

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Prostate Cancer Benign Prostatic Hypertrophy Bladder Stones Kidney Stones

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Prostate Cancer (PCa)

Comprised of men with biopsy-confirmed PCa who are scheduled for prostatectomy.

NV-VPAC1 PCa Urine Diagnostic Test

Intervention Type DIAGNOSTIC_TEST

The NV-VPAC1 PCa Urine Diagnostic Test is intended for use by clinicians to detect the presence of prostate cancer cells shed in voided urine of men at risk for prostate cancer.

Benign Prostatic Hypertrophy (BPH)

comprosed of men with benign prostatic hypertrophy (BPH) who are scheduled for transurethral resection of the prostate (TURP).

NV-VPAC1 PCa Urine Diagnostic Test

Intervention Type DIAGNOSTIC_TEST

The NV-VPAC1 PCa Urine Diagnostic Test is intended for use by clinicians to detect the presence of prostate cancer cells shed in voided urine of men at risk for prostate cancer.

Bladder/kidney stone

Comprised of men or women with bladder/kidney stones who are scheduled for a cystoscopy.

NV-VPAC1 PCa Urine Diagnostic Test

Intervention Type DIAGNOSTIC_TEST

The NV-VPAC1 PCa Urine Diagnostic Test is intended for use by clinicians to detect the presence of prostate cancer cells shed in voided urine of men at risk for prostate cancer.

Interventions

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NV-VPAC1 PCa Urine Diagnostic Test

The NV-VPAC1 PCa Urine Diagnostic Test is intended for use by clinicians to detect the presence of prostate cancer cells shed in voided urine of men at risk for prostate cancer.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Males 18-80 years of age
* Biopsy-confirmed prostate cancer
* Scheduled within 2 weeks for prostatectomy
* Signed informed consent


* Males 18-80 years of age
* Diagnosis of BPH made by clinical symptoms (e.g., enlarged prostate, dribbling urine stream, frequent and urgent urination)
* Scheduled within 2 weeks for TURP
* Signed informed consent


* Males or females 18-80 years of age
* Diagnosed with bladder/kidney stones
* Scheduled within 2 weeks for cystoscopy
* Signed informed consent

Exclusion Criteria

* Presence or history of another cancer diagnosis, with the exception of certain skin cancers
* Currently treated with finasteride (Proscar®, Propecia®), dutasteride (Avodart®) or anti-androgen therapy (Lupron®)
* Participated in a clinical study with an investigational drug within 2 weeks of the screening visit.

Subjects with benign prostatic hypertrophy


* Presence or history of any cancer diagnosis, with the exception of certain skin cancers
* Currently treated with finasteride (Proscar®, Propecia®) or dutasteride (Avodart®)
* Participated in a clinical study with an investigational drug within 2 weeks of the screening visit.

Subjects with bladder/kidney stones


* Presence or history of any cancer diagnosis, with the exception of certain skin cancers
* Participated in a clinical study with an investigational drug within 2 weeks of the screening visit.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NuView Diagnostics

UNKNOWN

Sponsor Role collaborator

Intermountain Health Care, Inc.

OTHER

Sponsor Role lead

Responsible Party

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JAY BISHOFF

Director of Intermountain Urological Institute

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jay Bishoff, MD

Role: PRINCIPAL_INVESTIGATOR

Intermountain Health Care, Inc.

Locations

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Intermountain Medical Center

Murray, Utah, United States

Site Status

Countries

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United States

Other Identifiers

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VPAC

Identifier Type: -

Identifier Source: org_study_id

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