Analytical Specificity of Bladder EpiCheck Test in Healthy Population and Urology Patients Without Prior History or Evidence of Bladder Cancer

NCT ID: NCT06020807

Last Updated: 2023-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

168 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-05

Study Completion Date

2020-01-08

Brief Summary

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This is a prospective study to establish the analytical specificity of Bladder EpiCheck test in urine samples from healthy population and urology patients without prior history or evidence of bladder cancer.

Detailed Description

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Conditions

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Non Muscle Invasive Bladder Cancer Non-Muscle Invasive Bladder Urothelial Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy

Healthy subjects and urology patients without prior history or evidence of bladder cancer

Bladder EpiCheck

Intervention Type DIAGNOSTIC_TEST

Bladder EpiCheckTM (EpiCheck) is a urine test for monitoring of recurrence of NMIBC based on analysis of 15 informative DNA methylation biomarkers.

Interventions

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Bladder EpiCheck

Bladder EpiCheckTM (EpiCheck) is a urine test for monitoring of recurrence of NMIBC based on analysis of 15 informative DNA methylation biomarkers.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age 22 or older
* Able to sign the informed consent form
* Normal, healthy subjects or subjects with one of the following conditions:

1. Benign non-genitourinary disease (e.g. heart disease)
2. Non-genitourinary cancers (e.g. lung, CRC, breast)
3. Genitourinary disease other than bladder cancer including:
4. Benign prostatic hyperplasia (BPH)
5. Microhematuria proven negative for bladder cancer through prior UCC evaluation
6. Inflammation/infection
7. Symptomatic sexually transmitted disease (STD)
8. Urinary tract stones
9. Genitourinary trauma
* Subjects with native bladder

Exclusion Criteria

* Known current or prior diagnosis of bladder cancer (non-muscle or muscle invasive)
* Currently in work-up due to suspicion of cancer of any kind
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nucleix Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Urology San Antonio

San Antonio, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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UC-Bladder EpiCheck-FDA-02

Identifier Type: -

Identifier Source: org_study_id

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