Genetic Polymorphism and Post Operative Nausea and Vomiting (PONV)
NCT ID: NCT03627780
Last Updated: 2021-05-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
300 participants
OBSERVATIONAL
2017-01-02
2020-03-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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PONV
Patients presenting with postoperative nausea and vomiting
DNA extraction
DNA will be extracted from white cells
no PONV
Patients not presenting with postoperative nausea and vomiting
DNA extraction
DNA will be extracted from white cells
Interventions
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DNA extraction
DNA will be extracted from white cells
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Fundação de Amparo à Pesquisa do Estado de São Paulo
OTHER_GOV
Instituto do Cancer do Estado de São Paulo
OTHER
Responsible Party
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Principal Investigators
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Angela M Sousa, phd
Role: PRINCIPAL_INVESTIGATOR
Instituto do Cancer do Estado de São Paulo
Locations
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Cancer Institute of the State of Sao Paulo - ICESP
São Paulo, São Paulo, Brazil
Cancer Institute of the State of Sao Paulo
São Paulo, São Paulo, Brazil
Countries
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References
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Hayase T, Sugino S, Moriya H, Yamakage M. TACR1 gene polymorphism and sex differences in postoperative nausea and vomiting. Anaesthesia. 2015 Oct;70(10):1148-59. doi: 10.1111/anae.13082. Epub 2015 May 27.
Wesmiller SW, Bender CM, Sereika SM, Ahrendt G, Bonaventura M, Bovbjerg DH, Conley Y. Association between serotonin transport polymorphisms and postdischarge nausea and vomiting in women following breast cancer surgery. Oncol Nurs Forum. 2014 Mar 1;41(2):195-202. doi: 10.1188/14.ONF.195-202.
Grigio TR, Furuya TK, Slullitel A, Murillo Carrasco AG, Uno M, Alves MJF, Carmona MJC, Sugino S, Chammas R, Sousa AM. Clinical, ethnic and genetic risk factors associated with postoperative nausea and vomiting in patients undergoing cancer surgery: a case-control study. Am J Transl Res. 2025 Apr 15;17(4):3235-3246. doi: 10.62347/DGRM3907. eCollection 2025.
Other Identifiers
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NP1127/2017
Identifier Type: -
Identifier Source: org_study_id
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