Nutritional Risk Screening Nutritional Support Gastrointestinal Cancer
NCT ID: NCT06018246
Last Updated: 2023-08-30
Study Results
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Basic Information
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COMPLETED
NA
624 participants
INTERVENTIONAL
2021-07-20
2023-07-30
Brief Summary
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Detailed Description
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Methods: A total of 302 patients with gastrointestinal tumors admitted to the First Hospital of Shanxi Medical University from July 2021 to June 2023 were selected.All patients underwent nutritional risk screening after admission and were divided into intervention group (NRS2002≥3 and PG=SGA≥4, n=204) and control group (NRS2002 \< 3 or PG=SGA \< 4 , n=98) according to the screening results.Different nutritional interventions were given to analyze the changes of NRS-2002 and PG-SGA scores between the two groups before and after propensity score matching, and compare the changes of dietary energy, dietary protein, total energy, total protein, body mass index (BMI), fat-free weight, walking time, grip strength and other nutritional indicators (hemoglobin, albumin, prealbumin) between the two groups.The effects of disease type and age on the results were compared by stratified analysis.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Intervention Group
1. Before operation：The patients' dietary intake was assessed by a 24-hour dietary review by a professional dietitian.According to the diet of the patients, the intervention was carried out by a professional nutritionist according to the five-step treatment mode of malnutrition.If the food intake cannot meet 60% of the daily requirement, the previous step of treatment is used, and it is adjusted at any time according to the situation of the patient.
2. After operation:Same as control group.
3. Out-of-hospital: Same as before operation.
4. Strengthening Health Education and psychological intervention:Dietitians need to strengthen health education and communicate with patients during the implementation of nutrition intervention.For patients who actively cooperate with treatment, dietitians can give encouragement.
5. Exercise Instruction:After the operation, according to the tolerance, the dietitian can instruct the patient to take a certain time walking every day.
Malnutrition five-step treatment model + conventional nutritional intervention
1. Before operation：Same as arm description.
2. After operation:Same as control group.
3. Out-of-hospital: Same as before operation.
4. Strengthening Health Education and psychological intervention:Dietitians need to strengthen health education and communicate with patients during the implementation of nutrition intervention.For patients who actively cooperate with treatment, dietitians can give encouragement.
5. Exercise Instruction:After the operation, according to the tolerance, the dietitian can instruct the patient to take a certain time walking every day, gradually increase the patient's muscle endurance and improve the body resistance.
Control Group
Routine nutrition support in department.Nutritionists will give patients routine parenteral nutrition support via peripheral or central vein 0-48 hours after surgery and then start enteral nutrition support 48-72 hours after surgery.Patients were initially given half of their enteral nutrition and the rest was supplemented with parenteral nutrition.After adaptation, the patient stopped parenteral nutrition and all nutrition came from enteral nutrition.After the patient's gastrointestinal function gradually recovered, the enteral nutrition could gradually decrease.At this time, nutritionists can let the patient eat some light liquid food, but pay attention to eating a small amount of multiple times.After adaptation, patients can gradually transition from liquid diet to semi-liquid diet.We will educate patients and their families about diet and encourage them to eat more high-quality protein-rich foods.
Conventional nutritional intervention
Routine nutrition support in department.Nutritionists will give patients routine parenteral nutrition support via peripheral or central vein 0-48 hours after surgery and then start enteral nutrition support 48-72 hours after surgery.Patients were initially given half of their enteral nutrition and the rest was supplemented with parenteral nutrition.After adaptation, the patient stopped parenteral nutrition and all nutrition came from enteral nutrition.After the patient's gastrointestinal function gradually recovered, the enteral nutrition could gradually decrease.At this time, nutritionists can let the patient eat some light liquid food, but pay attention to eating a small amount of multiple times.After adaptation, patients can gradually transition from liquid diet to semi-liquid diet.We will educate patients and their families about diet and encourage them to eat more high-quality protein-rich foods.
Interventions
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Malnutrition five-step treatment model + conventional nutritional intervention
1. Before operation：Same as arm description.
2. After operation:Same as control group.
3. Out-of-hospital: Same as before operation.
4. Strengthening Health Education and psychological intervention:Dietitians need to strengthen health education and communicate with patients during the implementation of nutrition intervention.For patients who actively cooperate with treatment, dietitians can give encouragement.
5. Exercise Instruction:After the operation, according to the tolerance, the dietitian can instruct the patient to take a certain time walking every day, gradually increase the patient's muscle endurance and improve the body resistance.
Conventional nutritional intervention
Routine nutrition support in department.Nutritionists will give patients routine parenteral nutrition support via peripheral or central vein 0-48 hours after surgery and then start enteral nutrition support 48-72 hours after surgery.Patients were initially given half of their enteral nutrition and the rest was supplemented with parenteral nutrition.After adaptation, the patient stopped parenteral nutrition and all nutrition came from enteral nutrition.After the patient's gastrointestinal function gradually recovered, the enteral nutrition could gradually decrease.At this time, nutritionists can let the patient eat some light liquid food, but pay attention to eating a small amount of multiple times.After adaptation, patients can gradually transition from liquid diet to semi-liquid diet.We will educate patients and their families about diet and encourage them to eat more high-quality protein-rich foods.
Eligibility Criteria
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Inclusion Criteria
2. The first pathological diagnosis was gastric or colorectal cancer and radical resection of malignant tumor was performed；
3. Conscious, able to read, write and understand the study；
4. Sign informed consent and participate in this study voluntarily.
Exclusion Criteria
2. Patients undergoing neoadjuvant chemotherapy before surgery；
3. Anastomotic fistula, anastomotic obstruction, gastroparesis and other serious complications occurred after operation；
4. There are mental disorders, psychological disorders；
5. Patients who did not cooperate to complete the full intervention or follow-up records were missing；
6. Patients with missing baseline data and nutritional risk screening results.
18 Years
ALL
No
Sponsors
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The First Affiliated Hospital of Shanxi Medical University
OTHER
Responsible Party
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Huang He
Chief physician of gastrointestinal surgery and Section chief of Medical Services Division
Principal Investigators
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He Huang, doctor's degree
Role: STUDY_DIRECTOR
The First Affiliated Hospital of Shanxi Medical University
Locations
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Huang He
Taiyuan, Shanxi, China
Countries
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Other Identifiers
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2022HLL003
Identifier Type: -
Identifier Source: org_study_id
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