The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

NCT ID: NCT00987883

Last Updated: 2009-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Study Completion Date

2009-12-31

Brief Summary

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Undernutrition is a state marked by energy and/or protein intake deficiency or mal-absorption, and is often described as protein energy malnutrition (PEM). Malnutrition is common in hospitalized patients worldwide. The prevalence of malnutrition in hospitalized patients range from 20% - 50%, depends on the varieties of diseases, health system, population and assessment tools. It is well documented in Western countries that malnutrition affects clinical outcomes negatively. Compared with well-nourished patients, patients with malnutrition stay longer in hospitals and related cost is significantly higher.

There is increasing evidence which indicates that appropriate nutrition support (e.g., standardized nutrition screening procedures, delivering nutrients with appropriate path, etc) may improve clinical outcome on malnutrition, along with cost saving.

To date, there is no study to document specifically the impact of malnutrition and related nutrition support on the health economics in China. Considering China now is on its way to establish public health security system and a diagnosis-related grouping system, the understanding of the cost effectiveness of nutrition support under the current clinical conditions is crucial.

This study aims to investigate the prevalence of perioperational malnutrition in gastroenterological cancer patient, the nutrition support status and related health economic effects.

Detailed Description

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Conditions

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Malnutrition Gastroenterological Cancer Surgical Procedures, Operative

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Malnutrition cohort

The patients with undernutrition

No interventions assigned to this group

Well nourished cohort

Patient that well nourished and without undernutrition

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age 18 or older
* With gastroenterological cancer
* Will receive resectional operation
* Consent informed

Exclusion Criteria

* With severly cardiac, pulmonary, liver or renal disease
* With endocrine or metabolic disease
* With dyslipidemia
* Without consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Peking Union Medical College Hospital

Principal Investigators

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Wei Chen, M.D

Role: STUDY_DIRECTOR

Peking Union Medical College Hospital

Chongmei Lu, M.D

Role: STUDY_CHAIR

Peking Union Medical College Hospital

Hua Jiang, M.D

Role: PRINCIPAL_INVESTIGATOR

Sichuan Academy of Medical Sciences

Locations

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Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Wei Chen, M.D

Role: CONTACT

86 10 65294095

Hua Jiang, M.D

Role: CONTACT

86 28 86741981

Facility Contacts

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Wei Chen, M.D

Role: primary

86 10 65294095

Hua Jiang, M.D

Role: backup

86 28 86741981

References

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Correia MI, Campos AC; ELAN Cooperative Study. Prevalence of hospital malnutrition in Latin America: the multicenter ELAN study. Nutrition. 2003 Oct;19(10):823-5. doi: 10.1016/s0899-9007(03)00168-0.

Reference Type BACKGROUND
PMID: 14559314 (View on PubMed)

Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease-related malnutrition. Clin Nutr. 2008 Feb;27(1):5-15. doi: 10.1016/j.clnu.2007.10.007. Epub 2007 Dec 3.

Reference Type BACKGROUND
PMID: 18061312 (View on PubMed)

Robinson G, Goldstein M, Levine GM. Impact of nutritional status on DRG length of stay. JPEN J Parenter Enteral Nutr. 1987 Jan-Feb;11(1):49-51. doi: 10.1177/014860718701100149.

Reference Type BACKGROUND
PMID: 3102782 (View on PubMed)

Lochs H, Allison SP, Meier R, Pirlich M, Kondrup J, Schneider S, van den Berghe G, Pichard C. Introductory to the ESPEN Guidelines on Enteral Nutrition: Terminology, definitions and general topics. Clin Nutr. 2006 Apr;25(2):180-6. doi: 10.1016/j.clnu.2006.02.007. Epub 2006 May 11.

Reference Type RESULT
PMID: 16697086 (View on PubMed)

Other Identifiers

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PUMCH-DPEN-09001

Identifier Type: -

Identifier Source: org_study_id

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