Effects of Basic Carbohydrate Counting Versus Standard Outpatient Nutritional Education in Type 2 Diabetes

NCT ID: NCT03623139

Last Updated: 2023-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-28

Study Completion Date

2022-08-16

Brief Summary

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The aim of the study is to examine the health benefits of adding a concept in basic carbohydrate counting (BCC) to the routine outpatient nutritional education for adult patients with type 2 diabetes.

The study hypothesis is that training and education in the BCC concept will improve glycaemic control either by reducing HbA1c or the average plasma glucose variability more than offering the routine dietary care as a stand-alone dietary treatment.

Detailed Description

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The trial has a parallel-group design with a study duration of 48 weeks for each participant (a 6-month intervention period and a 6-month follow-up period). A total of 226 patients will be enrolled in the trial. Participants will be randomized to one of two arms: 1) Standard medical and dietary care (control group) or 2) Structured training and education in the BCC concept in addition to standard medical and dietary care.

The primary objective is to evaluate the six months effect of structured training and education in the BCC concept compared to standard dietary care on glycaemic control as assessed by HbA1c or MAGE (mean amplitude of glycaemic excursions).

Conditions

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Type2 Diabetes Diabetes Mellitus, Type 2 Glucose Metabolism Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard nutritional education

Control group

Group Type ACTIVE_COMPARATOR

Standard nutritional education

Intervention Type BEHAVIORAL

Routine dietary care consists of three individual consultations with a trained dietitian. The individual guidance will be in accordance with the dietary guidelines in type 2 diabetes.

BCC

Education and training i basic carbohydrate counting (BCC) plus standard nutritional education

Group Type EXPERIMENTAL

Basic carbohydrate counting

Intervention Type BEHAVIORAL

The BCC concept is a group-based program consisting of three group sessions delivered by trained dietitians.

Interventions

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Standard nutritional education

Routine dietary care consists of three individual consultations with a trained dietitian. The individual guidance will be in accordance with the dietary guidelines in type 2 diabetes.

Intervention Type BEHAVIORAL

Basic carbohydrate counting

The BCC concept is a group-based program consisting of three group sessions delivered by trained dietitians.

Intervention Type BEHAVIORAL

Other Intervention Names

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Routine dietary care in type 2 diabetes Education in BCC in addition to standard dietary care

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetes
* Diabetes duration; from \>12 months
* HbA1c between 53 and 97 mmol/mol
* Diet or any glucose-lowering medication
* Provided voluntary written informed consent

Exclusion Criteria

* Practicing carbohydrate counting, as judged by the investigator
* Participated in a BCC group program within the last two years
* Low daily intake of carbohydrates (defined as below 25 E% or 100 g/day), as judged by the investigator
* Use of open CGM
* Use of a Free Libre device
* Use of an automated bolus calculator for carbohydrate counting, as judged by the investigator
* Gastroparesis
* Pregnancy or breastfeeding, or plans of pregnancy within the study period
* Uncontrolled medical issues, as judged by the investigator
* Concomitant participation in other clinical studies
* Unable to understand the informed consent and the study procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

Steno Diabetes Center Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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Bettina Ewers

Head of nutrition, MSc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bettina Ewers, MSc

Role: PRINCIPAL_INVESTIGATOR

Steno Diabetes Center Copenhagen

Locations

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Steno Diabetes Center Copenhagen

Herlev, , Denmark

Site Status

Countries

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Denmark

References

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Ewers B, Bruun JM, Vilsboll T. Effects of basic carbohydrate counting versus standard outpatient nutritional education (The BCC Study): study protocol for a randomised, parallel open-label, intervention study focusing on HbA1c and glucose variability in patients with type 2 diabetes. BMJ Open. 2019 Nov 21;9(11):e032893. doi: 10.1136/bmjopen-2019-032893.

Reference Type DERIVED
PMID: 31753900 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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H-18014918

Identifier Type: -

Identifier Source: org_study_id

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