The Effects of Nutritional Intervention on Health Parameters in Participants With Type 2 Diabetes Mellitus

NCT ID: NCT06235762

Last Updated: 2024-02-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-16

Study Completion Date

2023-12-15

Brief Summary

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The goal of this clinical trial is to evaluate the effects of nutritional intervention on anthropometric, biochemical and cardiovascular parameters in participants with type 2 diabetes mellitus. Participants will be distributed into 2 groups (control and intervention). Participants in the control group will only undergo conventional medical assessment and participants in the intervention group will receive the same medical care, concomitantly with nutritional assessment. The nutritional intervention is expected to reduce anthropometric data, glycemic and cardiovascular parameters in participants with T2DM, as opposed to the control group.

Detailed Description

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The goal of this clinical trial is: 1- Evaluate the effects of nutritional intervention on anthropometric parameters {Weight, Body Mass Index (BMI), Waist Circumference and Waist Hip Ratio (WHR)}, biochemical parameters {Fasting blood glucose, Glycated Hemoglobin (HBA1C), Total Cholesterol ( TC), LDL Cholesterol (LDL-C), HDL Cholesterol (HDL-C) and Triglycerides} and cardiovascular {Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and Heart Rate (HR)}. 2- Evaluate behavioral patterns related to lifestyle, such as skipping breakfast, sleep quality (induction, maintenance and awakenings) and frequency of physical activity. 3-Support knowledge to the participant to build eating autonomy, consequently improving quality of life in the long term.

This research will recruit participants diagnosed with T2DM (of both sexes aged between 18 and 80 years), at the Diabetes Outpatient Clinic and Hypertension at the Faculty of Medicine of São José do Rio Preto. The interventions will be distributed in quarterly meetings. Participants will be randomly distributed into 2 groups (control and the intervention group). The 40 participants in the control group will only undergo conventional medical evaluation and the 40 Participants in the intervention group will undergo the same medical care, concomitantly with nutritional assessment. Nutritional services will be made up of: A) Application of protocols (1-Nutritional History - Anthropometric, Biochemical and Clinical; 2-Habitual Food Record; 3-Sociodemographic protocol); B) Delivery of nutritional guidelines; C) Preparation of an individualized eating plan (inspired by the Mediterranean Diet and DASH diet with moderate carbohydrate content and restriction of saturated fats).

It is expected that interventions modulate the recovery of nutritional status, dietary inadequacies, parameters anthropometric, biochemical, cardiovascular and clinics, thus improving quality of life and reducing the risk of events in participants with T2DM in long term. In this way, the participants in treatment with nutritional support will be able to achieve greater benefit, maximizing the construction of a process of autonomy to feed.

Conditions

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Diabetes Mellitus Type 2 Diabetes Mellitus Type 2 in Obese Diabetes Diabetes Mellitus Non-insulin-dependent Hypertension Type 2 Diabetes Mellitus

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Ranzomized Clinical Trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Conventional Medical Evaluation

Participants in the control group will only undergo conventional medical evaluation.

Group Type NO_INTERVENTION

No interventions assigned to this group

Conventional Medical Evaluation Plus Nutritional Assessment

Participants in the intervention group will undergo the same medical care, concomitantly with nutritional assessment.

Group Type ACTIVE_COMPARATOR

Nutritional Intervention

Intervention Type BEHAVIORAL

This clinical trial evaluate the effects of nutritional intervention (individualized and personalized for each patient) on anthropometric, biochemical and cardiovascular parameters in participants with type 2 diabetes mellitus

Interventions

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Nutritional Intervention

This clinical trial evaluate the effects of nutritional intervention (individualized and personalized for each patient) on anthropometric, biochemical and cardiovascular parameters in participants with type 2 diabetes mellitus

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age: Adults above 18 years to below 80 years.
* Diagnosis of the disease: T2DM, that is, fasting blood glucose values equal to or greater than 126 mg/dL and glycated hemoglobin equal to or greater than 6.5%.
* Gender: Male and female
* Availability to participate in quarterly meetings during a period of 36 months.
* Nutritional status: initial diagnosis of overweight or obesity, that is, with BMI above 24.9kg/m².
* Sedentary.

Exclusion Criteria

* They had difficulties answering the requested instruments.
* They demonstrated impediments to assiduity in data collection.
* They did not present a diagnosis of T2DM.
* They were using insulin therapy.
* They were using SGLT-2 inhibitors and/or GLP-1 analogues.
* People with Chronic Kidney Disease.
* Eutrophic or malnourished.
* Physical exercisers, that is, more than 150 minutes of moderate to intense exercise per week.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

Sao Jose do Rio Preto Medical School

OTHER

Sponsor Role lead

Responsible Party

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Tatiana Palotta Minari

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tatiana Palotta Minari, PhD Student

Role: PRINCIPAL_INVESTIGATOR

State Faculty of Medicine in São José do Rio Preto

Locations

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Faculty of Medicine in São José do Rio Preto

São José do Rio Preto, São Paulo, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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33554520.0.0000.5415

Identifier Type: -

Identifier Source: org_study_id

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