Trial of Void With Saline Bladder Instillation

NCT ID: NCT03609476

Last Updated: 2020-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-24

Study Completion Date

2020-05-19

Brief Summary

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This study is being done to see if there is a difference between the traditional method of removing a urethral catheter after surgery and waiting for the patient to urinate on their own to the saline instillation method which places either room temperature or warmed saline into the patient's bladder through the catheter before removing the catheter.

Detailed Description

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Voiding trials after surgery to remove a catheter can be done in different ways.

Traditional method: The catheter is removed and the patient will attempt to void.

Room temperature saline instillation: Room temperature saline will be placed in the patients bladder through the catheter. The catheter will be removed and the patient will attempt to void.

Warmed saline group: Saline that has been warmed to 37C will be placed in the patients bladder through the catheter. The catheter will be removed and the patient will attempt to void.

Conditions

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Urethral Catheter Removal After Urologic Procedure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Standard of care group

No saline instillation

Group Type ACTIVE_COMPARATOR

No saline instillation

Intervention Type PROCEDURE

No saline is used prior to catheter removal

Room temperature saline group

room temperature saline instillation

Group Type ACTIVE_COMPARATOR

Room temperature saline instillation

Intervention Type PROCEDURE

Saline is used as room temperature

Warmed saline group

warmed saline instillation

Group Type ACTIVE_COMPARATOR

Warmed saline instillation

Intervention Type PROCEDURE

Saline is warmed to 37Celcius prior to instillation

Interventions

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Room temperature saline instillation

Saline is used as room temperature

Intervention Type PROCEDURE

Warmed saline instillation

Saline is warmed to 37Celcius prior to instillation

Intervention Type PROCEDURE

No saline instillation

No saline is used prior to catheter removal

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing trial of void after placement of indwelling urethral catheter after urologic procedure

Exclusion Criteria

* Patient incontinent at baseline.
* Patient has chronic indwelling urinary catheter or uses clean intermittent catheterization at home.
* Patient has documented neurogenic bladder.
* No trained person to administer the instillation or perform consent.
* Patient refusal to participate.
* Patient unable to give informed consent.
* Patient is a prisoner.
* Patient is pregnant.
* Patient unable to participate in notifying nursing of voids.
* Nursing is unable to measure post void residual with bladder scan machine secondary to body habitus or other anatomical abnormality.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ronald Kaufman, MD

OTHER

Sponsor Role lead

Responsible Party

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Ronald Kaufman, MD

Associate Professor of Surgery

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Ronald P Kaufman, Jr., MD

Role: PRINCIPAL_INVESTIGATOR

Albany Medical College, Division of Urology

Locations

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Albany Medical College

Albany, New York, United States

Site Status

Countries

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United States

References

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Baldini G, Bagry H, Aprikian A, Carli F. Postoperative urinary retention: anesthetic and perioperative considerations. Anesthesiology. 2009 May;110(5):1139-57. doi: 10.1097/ALN.0b013e31819f7aea.

Reference Type BACKGROUND
PMID: 19352147 (View on PubMed)

Emberton M, Fitzpatrick JM. The Reten-World survey of the management of acute urinary retention: preliminary results. BJU Int. 2008 Mar;101 Suppl 3:27-32. doi: 10.1111/j.1464-410X.2008.07491.x.

Reference Type BACKGROUND
PMID: 18307683 (View on PubMed)

Boccola MA, Sharma A, Taylor C, Wong LM, Travis D, Chan S. The infusion method trial of void vs standard catheter removal in the outpatient setting: a prospective randomized trial. BJU Int. 2011 Apr;107 Suppl 3:43-6. doi: 10.1111/j.1464-410X.2011.10044.x.

Reference Type BACKGROUND
PMID: 21492377 (View on PubMed)

Du J, Marshall D, Leyland J, Shaw L, Broome KE, Mason DF. Prospective, multicentre, randomized controlled trial of bladder filling prior to trial of void on the timing of discharge. ANZ J Surg. 2013 Apr;83(4):239-42. doi: 10.1111/j.1445-2197.2012.06253.x. Epub 2012 Sep 18.

Reference Type BACKGROUND
PMID: 22984818 (View on PubMed)

Wilson ID, Bramwell SP, Hollins GW. A randomized trial comparing bladder infusion with standard catheter removal after transurethral resection of the prostate. BJU Int. 2000 Dec;86(9):993-5. doi: 10.1046/j.1464-410x.2000.00963.x.

Reference Type BACKGROUND
PMID: 11119091 (View on PubMed)

Foster RT Sr, Borawski KM, South MM, Weidner AC, Webster GD, Amundsen CL. A randomized, controlled trial evaluating 2 techniques of postoperative bladder testing after transvaginal surgery. Am J Obstet Gynecol. 2007 Dec;197(6):627.e1-4. doi: 10.1016/j.ajog.2007.08.017.

Reference Type BACKGROUND
PMID: 18060956 (View on PubMed)

Pulvino JQ, Duecy EE, Buchsbaum GM, Flynn MK. Comparison of 2 techniques to predict voiding efficiency after inpatient urogynecologic surgery. J Urol. 2010 Oct;184(4):1408-12. doi: 10.1016/j.juro.2010.05.096. Epub 2010 Aug 19.

Reference Type BACKGROUND
PMID: 20727543 (View on PubMed)

Lyth DR, Braslis K, Iacovou JW. The infusion trial of micturition. Br J Urol. 1997 Jan;79(1):94-5. doi: 10.1046/j.1464-410x.1997.30520.x.

Reference Type BACKGROUND
PMID: 9043505 (View on PubMed)

Noble JG, Menzies D, Cox PJ, Edwards L. Midnight removal: an improved approach to removal of catheters. Br J Urol. 1990 Jun;65(6):615-7. doi: 10.1111/j.1464-410x.1990.tb14830.x.

Reference Type BACKGROUND
PMID: 2372674 (View on PubMed)

Crowe H, Clift R, Duggan G, Bolton D, Costello A. Randomized study of the effect of midnight removal of urinary catheters. Urol Nurs. 1994 Mar;14(1):18-20.

Reference Type BACKGROUND
PMID: 8153735 (View on PubMed)

Zimlichman E, Henderson D, Tamir O, Franz C, Song P, Yamin CK, Keohane C, Denham CR, Bates DW. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med. 2013 Dec 9-23;173(22):2039-46. doi: 10.1001/jamainternmed.2013.9763.

Reference Type BACKGROUND
PMID: 23999949 (View on PubMed)

Richards MJ, Edwards JR, Culver DH, Gaynes RP. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol. 2000 Aug;21(8):510-5. doi: 10.1086/501795.

Reference Type BACKGROUND
PMID: 10968716 (View on PubMed)

Klevens RM, Edwards JR, Richards CL Jr, Horan TC, Gaynes RP, Pollock DA, Cardo DM. Estimating health care-associated infections and deaths in U.S. hospitals, 2002. Public Health Rep. 2007 Mar-Apr;122(2):160-6. doi: 10.1177/003335490712200205.

Reference Type BACKGROUND
PMID: 17357358 (View on PubMed)

Maki DG, Tambyah PA. Engineering out the risk for infection with urinary catheters. Emerg Infect Dis. 2001 Mar-Apr;7(2):342-7. doi: 10.3201/eid0702.010240.

Reference Type BACKGROUND
PMID: 11294737 (View on PubMed)

Stenzelius K, Persson S, Olsson UB, Stjarneblad M. Noble metal alloy-coated latex versus silicone Foley catheter in short-term catheterization: a randomized controlled study. Scand J Urol Nephrol. 2011 Sep;45(4):258-64. doi: 10.3109/00365599.2011.560007. Epub 2011 Mar 31.

Reference Type BACKGROUND
PMID: 21452931 (View on PubMed)

Gould CV, Umscheid CA, Agarwal RK, Kuntz G, Pegues DA; Healthcare Infection Control Practices Advisory Committee. Guideline for prevention of catheter-associated urinary tract infections 2009. Infect Control Hosp Epidemiol. 2010 Apr;31(4):319-26. doi: 10.1086/651091. No abstract available.

Reference Type BACKGROUND
PMID: 20156062 (View on PubMed)

Hooton TM, Bradley SF, Cardenas DD, Colgan R, Geerlings SE, Rice JC, Saint S, Schaeffer AJ, Tambayh PA, Tenke P, Nicolle LE; Infectious Diseases Society of America. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis. 2010 Mar 1;50(5):625-63. doi: 10.1086/650482.

Reference Type BACKGROUND
PMID: 20175247 (View on PubMed)

Tambyah PA, Oon J. Catheter-associated urinary tract infection. Curr Opin Infect Dis. 2012 Aug;25(4):365-70. doi: 10.1097/QCO.0b013e32835565cc.

Reference Type BACKGROUND
PMID: 22691687 (View on PubMed)

Glynn A WV, Wilson J, et al. Hospital acquired infection: surveillance, policies and practice-a study of the control of hospital acquired infection in hospitals in England and Wales. In: Service PHL, ed. London1997.

Reference Type BACKGROUND

Other Identifiers

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AMC4851

Identifier Type: -

Identifier Source: org_study_id

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