Total Knee Arthroplasty Robot Assisted With MAKO™ Robotic System Compared to the Conventional Total Knee Arthroplasty by Mechanical Ancillary

NCT ID: NCT03566875

Last Updated: 2020-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-23

Study Completion Date

2020-09-23

Brief Summary

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For the total knee arthrorplasty (TKA), the placement of a prosthesis is delicate and the correct positioning of the implants determines the result of the surgery.

Navigation has improved surgical accuracy but remains inadequate with nearly 20% malposition. In the early 2010s, robot-assisted surgery solutions were born. Amongst its offers, Stryker's MAKO™ system appears to be the most advanced and developed due to its precision and its flexibility of use during surgery.

In this study, the investigators evaluate the placement of the total knee prosthesis with the MAKO™ system compared to the placement of the total knee prosthesis with a conventional mechanical system for TKA

Detailed Description

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Conditions

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Total Knee Arthroplasty

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Total knee arthroplasty with the Stryker's MAKO™ system

The total knee arthroplasty is performed with Stryker's MAKO™ robotic system. It allows to place precisely the prosthetic implants.

Group Type EXPERIMENTAL

Total knee arthroplasty with the Stryker's MAKO™ system

Intervention Type PROCEDURE

The robot assisted surgery is performed using the Stryker's MAKO™ system. The precision with this system is very accurate. It should help the surgeon to improve the positioning accuracy of prosthetic implants compared to the conventional method.

Total knee arthroplasty with mechanical ancillary

The total knee arthroplasty is performed using a mechanical ancillary. It's the conventional method.

Group Type ACTIVE_COMPARATOR

Total knee arthroplasty with mechanical ancillary

Intervention Type PROCEDURE

The arthroplasty is performed with the mechanical ancillary refering to the the conventional method.

Interventions

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Total knee arthroplasty with the Stryker's MAKO™ system

The robot assisted surgery is performed using the Stryker's MAKO™ system. The precision with this system is very accurate. It should help the surgeon to improve the positioning accuracy of prosthetic implants compared to the conventional method.

Intervention Type PROCEDURE

Total knee arthroplasty with mechanical ancillary

The arthroplasty is performed with the mechanical ancillary refering to the the conventional method.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Major patient
* Patient who must have a total prosthetic knee surgery at CHUGA with the useful indications : painful and disabling knee joint disease: traumatic arthritis or avascular necrosis, rheumatoid arthritis or post-traumatic arthritis, post-traumatic loss of the configuration and function of the knee joint, moderate deformities in varus, or valgus or flexion in ligamentous structures can find a function and a fracture of the distal femur and / or proximal tibia that can not be stabilized by standard fracture management techniques.
* Social security affiliates or beneficiaries of a scheme

Exclusion Criteria

* refusal of consent,
* patient with a contraindication to prosthetic knee surgery:
* any active or suspected latent infection in or around the knee joint,
* remote foci of infection that can cause haematogenous spread on the implant site,
* any mental or neuromuscular disorder that would create an unacceptable risk of instability of the prosthesis,
* failure of prosthesis fixation or complications in postoperative care,
* a bone stock compromised by a disease,
* infection or anterior prosthetic implantation that can not provide adequate support and / or satisfactory fixation to the prosthesis,
* skeletal immaturity,
* severe instability of the knee joint secondary to the lack of integrity and function of the collateral ligament,
* woman of childbearing age,
* patient during the exclusion period of another study,
* patient referred in Articles L1121-5 to L1121-8 of the Public Health Code
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Clinical Investigation Centre for Innovative Technology Network

NETWORK

Sponsor Role collaborator

Stryker Orthopaedics

INDUSTRY

Sponsor Role collaborator

University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Régis Pailhé, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire Grenoble-Alpes

Locations

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University Grenoble Hospital

Échirolles, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Régis Pailhé, MD, PhD

Role: CONTACT

+33 617970492

Emilie Chipon, PhD

Role: CONTACT

+33 476767313

Facility Contacts

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Régis PI Pailhé, PhD

Role: primary

04 76 76 75 75

Emilie CEC Chipon, PhD

Role: backup

04 76 76 73 13

Other Identifiers

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38RC17.373

Identifier Type: -

Identifier Source: org_study_id

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