Acute Kidney Injury in Neonates at NICU in Assiut University Children Hospital Descriptive Study

NCT ID: NCT03528837

Last Updated: 2018-05-18

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-06-30
• Study Completion Date: 2019-08-01

Brief Summary

Acute kidney injury (AKI) is a complex disorder with clinical manifestations ranging from mild dysfunction to complete anuric kidney failure. Its leads to sudden and rapid decline in renal excretory function within hours to days,accompanied by accumulation of nitrogenous waste products such creatinine,urea and other clinically un measured products

Detailed Description

Acute kidney injury (AKI) is an under-recognized morbidity of neonates; the incidence remains unclear due to the absence of a unified definition of AKI in this population and because previous studies have varied greatly in screening for AKI with serum creatinine and urine output assessments. Premature infants may be born with less than half of the nephrons compared with term neonates, predisposing them to chronic kidney disease (CKD) early on in life and as they age. AKI can also lead to CKD, and premature infants with AKI may be at very high risk for long-term kidney problems. AKI in neonates is often multifactorial and may result from prenatal, perinatal, or postnatal insults as well as any combination thereof.

Conditions

Neonatal Acute Kidney Injury

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

Diagnosed as acute kidney injury

Sure diagnosed as acute kidney injury

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• All cases of acute kidney injury in neonates who will be admitted to NICU Assiut University Children Hospital during the duration of the study.

Exclusion Criteria

• Cases with chronic renal affection Any case with congenital anomalies

• Minimum Eligible Age: 1 Day
• Maximum Eligible Age: 28 Days
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Ali Abdelrhman

Resident of neonatology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Assiut university children hospital

Asyut, , Egypt

Countries

Egypt

Central Contacts

Mustafa Sh Khalf, Professor

Role: CONTACT

mostafa.tawfeek1@med.au.edu.eg

+20112110096

Ahlam B Ali, Lectuer

Role: CONTACT

+201006807866

Facility Contacts

Mostafa Sh Khalf, Bachlear

Role: primary

mostafa.tawfeek1@med.au.edu.eg

+201112110096

Other Identifiers

AKI neonates

Identifier Type: -

Identifier Source: org_study_id