A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

NCT ID: NCT03504358

Last Updated: 2018-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

129 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-01

Study Completion Date

2017-12-31

Brief Summary

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Develop a new scoring system for HCC patients with tumor rupture.

Detailed Description

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There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Conditions

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Rupture, Spontaneous

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Analysis before liver resection

Multivariate analysis of predictive factors associated with survival

Liver resection

Intervention Type PROCEDURE

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Different risk group

Low-risk group, moderate-risk group, high-risk group

Liver resection

Intervention Type PROCEDURE

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Model comparison

Comparison of models in predicting survival

Liver resection

Intervention Type PROCEDURE

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Interventions

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Liver resection

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Received partial hepatectomy; with Child A or B liver function.

Exclusion Criteria

* Without complete data;loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.
Minimum Eligible Age

15 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Xiaoping Chen

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bi-xiang Zhang, Prof, PHD

Role: STUDY_CHAIR

Huazhong University of Science and Technology

Other Identifiers

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Zhupeng002

Identifier Type: -

Identifier Source: org_study_id

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