A Comparison Between Child-Pugh and Albumin-Bilirubin Scores

NCT ID: NCT03534843

Last Updated: 2018-05-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

230 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-01-01

Study Completion Date

2018-01-01

Brief Summary

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To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma

Detailed Description

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To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma. And to determine which is better in predicting long-term survival and short-term survival.

Conditions

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Rupture, Spontaneous Rupture Liver Hepatocellular Carcinoma Hepatic Impairment

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Surgical treatment

Patients who received liver resection or palliative surgery, such as microwave coagulation therapy, hepatic artery ligation, or suturing ligation.

Liver resection

Intervention Type PROCEDURE

Liver resection was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Non-surgical treatment

Patients who received transcatheter arterial embolization (or transcatheter arterial chemoembolization) or conservative treatment

Transcatheter arterial embolization

Intervention Type OTHER

Transcatheter arterial embolization or transcatheter arterial chemoembolization can localize the bleeding point and provide interventional embolization.

Interventions

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Liver resection

Liver resection was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Intervention Type PROCEDURE

Transcatheter arterial embolization

Transcatheter arterial embolization or transcatheter arterial chemoembolization can localize the bleeding point and provide interventional embolization.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Be diagnosed as hepatocellular carcinoma pathologically; had a tumor rupture confirmed by Intraperitoneal exploration or clinical signs and symptoms in combination with imaging examination.

Exclusion Criteria

* Be diagnosed as not hepatocellular carcinoma pathologically;had repeated transcatheter arterial chemoembolization(TACE) or a long history (more than 1 year) of cancer treatment; loss of follow up or without complete data.
Minimum Eligible Age

15 Years

Maximum Eligible Age

76 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Xiaoping Chen

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Xiao-ping Chen, Prof. PHD

Role: STUDY_CHAIR

Huazhong University of Science and Technology

References

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Wu JJ, Zhang ZG, Zhu P, Mba'nbo-Koumpa AA, Zhang BX, Chen XP, Shu C, Zhang WG, Feng RJ, Li GX. Comparative liver function models for ruptured hepatocellular carcinoma: A 10-year single center experience. Asian J Surg. 2019 Sep;42(9):874-882. doi: 10.1016/j.asjsur.2018.12.015. Epub 2019 Jan 28.

Reference Type DERIVED
PMID: 30704966 (View on PubMed)

Other Identifiers

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Chenxp011

Identifier Type: -

Identifier Source: org_study_id

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