ALBI and PALBI Scores and HCC Prognosis

NCT ID: NCT05720195

Last Updated: 2023-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

645 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2022-12-31

Brief Summary

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To compare the predictive ability of ALBI and PALBI grades with CTP and MELD scores.

To investigate the efficacy of ALBI and PALBI grades for predicting the prognosis of HCC and overall survival among different modalities of treatment.

Detailed Description

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Conditions

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Hepatocellular Carcinoma (HCC) Prognosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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ALBI

Albumin-Bilirubin and Platelet-Albumin-Bilirubin Grades for prognosis of HCC

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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PALBI

Eligibility Criteria

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Inclusion Criteria

• The diagnosis of HCC will be based on the presence of an arterial hypervascular focal lesion \> 2 cm with rapid wash-out with a single imaging modality (triphasic computed tomography (CT), or dynamic magnetic resonance imaging (MRI)) or two imaging modalities demonstrating the before mentioned feature for lesions \< 2 cm with or without elevated serum alpha-fetoprotein (AFP) levels.

Exclusion Criteria

* Patients below 18 years old.
* Patients with pre-existing other malignancies.
* Patients with pre-existing gall bladder stones, benign strictures, or other biliary diseases.
* Patients with pre-existing haematologic disorders.
* Patients with proteinuria.
* Missed follow-up.
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abudeif Abdelaal, MD

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag University

Sohag, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Soh-Med-21-10-41

Identifier Type: -

Identifier Source: org_study_id

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