Effect of I/R Injuries by Pringle Manoeuvre on the Prognosis of HCC Patients After Curative Hepatectomy
NCT ID: NCT00725335
Last Updated: 2012-11-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
498 participants
INTERVENTIONAL
2008-09-30
2012-11-30
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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group A,non-pringle group
Intervention of curative resection of HCC Without pringle manoeuvre in this arm
curative resection without Pringle
Radical excision of liver cancer without the procedure of pringle manoeuvre
pringle group(B)
when the curative resection of HCC performed, the pringle manoeuvre will be routinely applied.
curative resection with Pringle manoeuvre
curative resection liver cancer under pringle manoeuvre
Interventions
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curative resection without Pringle
Radical excision of liver cancer without the procedure of pringle manoeuvre
curative resection with Pringle manoeuvre
curative resection liver cancer under pringle manoeuvre
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* The liver function showed:Child-Pugh A，ICG-R15 \< 20%
* HbsAg (+)
* tumor nodes in the liver were singular or multiple and could be radical excision
* No preoperative anti-cancer therapy
* Written informed consent from the patient or legal guardian prior to entering the study
Exclusion Criteria
* With extrahepatic tumor or lymphnode metastasis
* Tumor invasion or thrombosis in portal vein,hepatic vein or inferior vena cava
* Positive marginal
18 Years
65 Years
ALL
No
Sponsors
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Chinese PLA General Hospital
OTHER
Fudan University
OTHER
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
OTHER
First Affiliated Hospital, Sun Yat-Sen University
OTHER
Southwest Hospital, China
OTHER
Responsible Party
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feng xiaobin
Dr Feng xiaobin
Principal Investigators
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Dong Jiahong, Ph D
Role: STUDY_DIRECTOR
Institue of hepatobiliary surgery,Chinese PLA General Hospital
Locations
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Institute of hepatobiliary surgery,southwest hospital
Chongqing, Chongqing Municipality, China
Countries
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References
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Xiaobin F, Shuguo Z, Jian Z, Yudong Q, Lijian L, Kuansheng M, Xiaowu L, Feng X, Dong Y, Shuguang W, Ping B, Jiahong D. Effect of the pringle maneuver on tumor recurrence of hepatocellular carcinoma after curative resection (EPTRH): a randomized, prospective, controlled multicenter trial. BMC Cancer. 2012 Aug 3;12:340. doi: 10.1186/1471-2407-12-340.
Related Links
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Other Identifiers
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ISRCTN01960869
Identifier Type: OTHER
Identifier Source: secondary_id
SWHB001
Identifier Type: -
Identifier Source: org_study_id