Neural Mechanisms of Decision Making in Hoarding Disorder

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

25 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-08

Study Completion Date

2026-05-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to understand the neural mechanisms of decision making in hoarding disorder.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Neural Mechanisms of CBT Response in Hoarding Disorder

NCT01956344

Obsessive Compulsive Disorder

COMPLETED NA

Unique Electroencephalography (EEG) Markers of Habit Behaviors in Obsessive-Compulsive Disorder (OCD)

NCT06882902

Obsessive-Compulsive Disorder

ENROLLING_BY_INVITATION NA

Compensatory Brain Mechanisms for Amygdala-associated Cognitive Dysfunction: Potential Role of the Cortical Mirror Neuron System

NCT03723733

Healthy

UNKNOWN

Attentional Capture by Real-life Episodic Information

NCT06934902

Healthy Volunteers Attentional Capture

NOT_YET_RECRUITING NA

Investigating the Specificity of Neural Correlates for Emotion Processing Deficits in Conduct Disorder and Autism Spectrum Disorders

NCT04324099

Autism-Spectrum Disorder Conduct Disorder

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Hoarding disorder is a common and disabling disorder that represents a significant public health problem. This study aims to build on current research on decision making by examining these processes in hoarding disorder.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hoarding Disorder

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Hoarding Disorder

Adults diagnosed with Hoarding Disorder

MRI with fMRI frequency

Intervention Type DEVICE

Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Healthy Controls

Adults without mental illness

MRI with fMRI frequency

Intervention Type DEVICE

Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MRI with fMRI frequency

Functional magnetic resonance imaging or fMRI measures brain activity by detecting changes in blood flow. Participants will do cognitive tasks during fMRI.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. ages 18-70
2. primary diagnosis of hoarding disorder
3. sufficient severity of hoarding symptoms
4. stable on psychotropic medications for 1 month prior to study enrollment
5. capacity to provide informed consent
6. ability to tolerate clinical study procedures

1. ages 18-70
2. capacity to provide informed consent

Exclusion Criteria

1. psychiatric or medical conditions that make participation unsafe
2. pregnant or nursing females
3. concurrent use of any medications that might increase the risk of participation (e.g. drug interactions)
4. presence of metallic device or dental braces

1. any current or lifetime psychiatric diagnosis
2. current or past use of psychotropic medication
3. pregnant or nursing females
4. major medical or neurological problem
5. presence of metallic device or dental braces

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes