Metabolic Dynamics During Physical Activity

NCT ID: NCT03485716

Last Updated: 2018-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-08-01

Study Completion Date

2017-12-31

Brief Summary

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The aim of this study is to systematically Analyse the metabolome in capillary blood of healthy men and women at rest and during defined standardized physical activity under normobaric normoxia or hypoxia with a specific focus on metabolites and metabolic pattern related to energy metabolism. The metabolome analyses in capillary blood could give us also or more detailed insight into erythrocyte metabolic physiology because it is known for a longer time that the primary metabolism of the erythrocyte reflects its Oxygen Saturation via the glycolytic metabolites / intermediates pattern.

Detailed Description

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Conditions

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Healthy Men and Women

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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running under hypoxia - first

running under hypoxia (first day) and normoxia (second day)

Group Type EXPERIMENTAL

running on a treadmill under normoxia or hypoxia

Intervention Type OTHER

* 30 min running (60% VO2max) on a treadmill under hypoxia (O2: 14%)
* 30 min running (60% VO2max) on a treadmill under normoxia (O2: 20%)

running under normoxia - first

running under normoxia (first day) and hypoxia (second day)

Group Type ACTIVE_COMPARATOR

running on a treadmill under normoxia or hypoxia

Intervention Type OTHER

* 30 min running (60% VO2max) on a treadmill under hypoxia (O2: 14%)
* 30 min running (60% VO2max) on a treadmill under normoxia (O2: 20%)

Interventions

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running on a treadmill under normoxia or hypoxia

* 30 min running (60% VO2max) on a treadmill under hypoxia (O2: 14%)
* 30 min running (60% VO2max) on a treadmill under normoxia (O2: 20%)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* healthy volunteers
* written informed consent

Exclusion Criteria

* known cardio-vascular, lung, metabolic, endocrine, hematologic, kidney or neurologic diseases
* pregnancy, lactating period
* unability to understand study content and aims and to give written informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Michael Boschmann

Dr. Michael Boschmann

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Michael Boschmann, Dr.

Role: PRINCIPAL_INVESTIGATOR

Charite University, Berlin, Germany

Locations

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Charite University Medicine, ECRC

Berlin, , Germany

Site Status

Countries

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Germany

Other Identifiers

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Hypoxitrain 2

Identifier Type: -

Identifier Source: org_study_id

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