Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
NCT ID: NCT03462706
Last Updated: 2023-02-15
Study Results
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View full resultsBasic Information
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COMPLETED
NA
238 participants
INTERVENTIONAL
2018-02-06
2021-05-14
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Cold Snare
Polyps sized 6mm to 15mm found during colonoscopy will be removed using cold snare techniques.
Cold Snare
Subjects randomized to Cold Snare Intervention will have any polyps sized 6mm to 15mm removed using cold snare techniques (no electrocautery, no submucosal injection.)
Hot Snare
Polyps sized 6mm to 15mm found during colonoscopy will be removed using hot snare techniques.
Hot Snare
Subjects randomized to Hot Snare Intervention will have any polyps sized 6mm to 15mm removed using hot snare techniques (with electrocautery, no submucosal injection.)
Cold EMR
Polyps sized 6mm to 15mm found during colonoscopy will be removed using cold EMR techniques.
Cold EMR
Subjects randomized to Cold EMR will have any polyps sized 6mm to 15mm removed using cold EMR techniques (no electrocautery, with submucosal injection.)
Hot EMR
Polyps sized 6mm to 15mm found during colonoscopy will be removed using hot EMR techniques.
Hot EMR
Subjects randomized to Hot EMR will have any polyps sized 6mm to 15mm removed using hot EMR techniques (with electrocautery, with submucosal injection.)
Interventions
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Cold Snare
Subjects randomized to Cold Snare Intervention will have any polyps sized 6mm to 15mm removed using cold snare techniques (no electrocautery, no submucosal injection.)
Hot Snare
Subjects randomized to Hot Snare Intervention will have any polyps sized 6mm to 15mm removed using hot snare techniques (with electrocautery, no submucosal injection.)
Cold EMR
Subjects randomized to Cold EMR will have any polyps sized 6mm to 15mm removed using cold EMR techniques (no electrocautery, with submucosal injection.)
Hot EMR
Subjects randomized to Hot EMR will have any polyps sized 6mm to 15mm removed using hot EMR techniques (with electrocautery, with submucosal injection.)
Eligibility Criteria
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Inclusion Criteria
* Ability to provide informed consent
Exclusion Criteria
* Lesions less than 6mm or greater than 15mm in largest dimension
40 Years
ALL
Yes
Sponsors
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John D. Dingell VA Medical Center
FED
White River Junction Veterans Affairs Medical Center
FED
Indiana University
OTHER
Responsible Party
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Douglas K. Rex
Professor of Medicine
Principal Investigators
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Douglas K Rex, MD
Role: PRINCIPAL_INVESTIGATOR
Indiana University
Locations
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Indiana University
Indianapolis, Indiana, United States
Countries
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References
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Rex DK, Anderson JC, Pohl H, Lahr RE, Judd S, Antaki F, Lilley K, Castelluccio PF, Vemulapalli KC. Cold versus hot snare resection with or without submucosal injection of 6- to 15-mm colorectal polyps: a randomized controlled trial. Gastrointest Endosc. 2022 Aug;96(2):330-338. doi: 10.1016/j.gie.2022.03.006. Epub 2022 Mar 12.
Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Other Identifiers
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1711062130
Identifier Type: -
Identifier Source: org_study_id
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