OKS for the Treatment of Hemispatial Neglect

NCT ID: NCT03451708

Last Updated: 2024-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-01

Study Completion Date

2023-03-31

Brief Summary

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Hemispatial neglect is a disorder where the patient has difficulty attending to objects and information in the left side of space, which occurs following strokes to the right side of the brain. This project is designed to help us understand how optokinetic stimulation treats the symptoms of hemispatial neglect.

Detailed Description

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Conditions

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Neglect, Hemispatial Neglect, Sensory Neglect, Hemisensory

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Patient blinded

Study Groups

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Optimization of OKS

Crossover study examining various OKS protocols on improving symptoms of hemispatial neglect

Group Type EXPERIMENTAL

OKS

Intervention Type DEVICE

Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects.

Safety and efficacy study

Randomized study assessing the safety and efficacy of OKS in treating hemispatial neglect

Group Type EXPERIMENTAL

OKS

Intervention Type DEVICE

Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects.

Effect of repetitive stimulation

Benefits of daily, repetitive OKS in treating hemispatial neglect

Group Type EXPERIMENTAL

OKS

Intervention Type DEVICE

Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects.

OKS and gait

Effect of OKS on gait and balance

Group Type EXPERIMENTAL

OKS

Intervention Type DEVICE

Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects.

Interventions

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OKS

Optokinetic stimulation will be displayed on a see-through liquid crystal display lens placed in front of the subjects.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with right hemispheric lesions resulting in hemispatial neglect as confirmed by Behavioral Inattention Test or Center of Cancellation Test

Exclusion Criteria

* Reduced vision
* Documented vestibular disorder
Minimum Eligible Age

21 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Johns Hopkins University

OTHER

Sponsor Role collaborator

National Eye Institute (NEI)

NIH

Sponsor Role collaborator

Beth Israel Deaconess Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Chun Lim

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chun Lim, MD

Role: PRINCIPAL_INVESTIGATOR

Beth Israel Deaconess Medical Center

Locations

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Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Longley V, Hazelton C, Heal C, Pollock A, Woodward-Nutt K, Mitchell C, Pobric G, Vail A, Bowen A. Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury. Cochrane Database Syst Rev. 2021 Jul 1;7(7):CD003586. doi: 10.1002/14651858.CD003586.pub4.

Reference Type DERIVED
PMID: 34196963 (View on PubMed)

Other Identifiers

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R21EY027468

Identifier Type: NIH

Identifier Source: secondary_id

View Link

2016P000396

Identifier Type: -

Identifier Source: org_study_id

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