Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation

NCT ID: NCT07227844

Last Updated: 2025-11-13

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 5 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-12-31
• Study Completion Date: 2026-12-31

Brief Summary

Neglect, a common and disabling neurological deficit post-CNS injury, profoundly hinders recovery and escalates healthcare costs. Current diagnostic tools are often insensitive or impractical, and while therapies exist, a significant research gap remains. Traditional methods, including standardized scales and paper-pencil tests, lack precision; even advanced video oculography is limited by cost and accessibility. Rehabilitative approaches like visual scanning and prism adaptation offer some benefit, but more effective solutions are needed. This project utilizes a non-invasive neuromodulatory training approach via a mixed-reality visual attention task delivered through a virtual reality headset. This system aims to improve both neglect diagnosis and personalized therapeutic intervention. The study will assess the headset's safety and practicality, its capacity to detect and lateralize neglect, and its long-term effect on improving attention to the neglected field. By measuring reaction times to visual stimuli within the VR environment, the research seeks to develop a more accessible and impactful tool for both assessing and treating neglect, potentially enabling self-directed therapy and enhancing patient outcomes.

Conditions

Neglect, Sensory; Neglect, Hemispatial; Neglect, Hemisensory

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Treatment

Group Type: EXPERIMENTAL

VR Neglect Training

Intervention Type: DEVICE

VR Neglect Training

Interventions

VR Neglect Training

VR Neglect Training

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• The study will involve patients over the age of 18 who have been diagnosed with a neurological injury that includes: ischemic stroke, hemorrhagic stroke, tumor, or trauma.
• Neurological injury that localizes to only one side of the brain
• At least one hand that retains dexterity enough to use a controller to extinguish the visual stimulus.
• Cognitive ability to understand simple instructions on how to use the device
• Visual fields intact

Exclusion Criteria

• Bilateral symptomatic injury
• Inability to consent or to comply with study
• Blindness or severe visual deficits other than neglect

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Markey Olson

OTHER

Sponsor Role: lead

Responsible Party

Markey Olson

Research Manager

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Barrow Neurological Institute

Phoenix, Arizona, United States

Countries

United States

Central Contacts

Markey Olson, PhD

Role: CONTACT

neuromodulationresearch@commonspirit.org

602-406-5944

Facility Contacts

Markey Olson, PhD

Role: primary

neuromodulationresearch@commonspirit.org

602-406-5944

Other Identifiers

26-500-131-30-06

Identifier Type: -

Identifier Source: org_study_id