Hemopatch Performance Evaluation: A Prospective Observational Registry

NCT ID: NCT03392662

Last Updated: 2022-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

621 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-29

Study Completion Date

2019-01-28

Brief Summary

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To assess the clinical performance and safety of HEMOPATCH Sealing Hemostat in a post-marketing setting in cardiovascular, thoracic, urologic, neurological, and other general surgical procedures.

Detailed Description

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Conditions

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Dura Mater Nick Cut or Tear Hemostatis Air Leakage Body Fluid Leakage

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hemopatch Sealant Use with Hepatobiliary Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Hemopatch Sealant Use with General Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Hemopatch Sealant Use with Lung Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Hemopatch Sealant Use with Cardiovascular Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Hemopatch Sealant Use with Neurological/Spinal Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Hemopatch Sealant Use with Urologic Surgery

Hemopatch

Intervention Type DEVICE

Patients received product at the discretion of their surgeon.

Interventions

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Hemopatch

Patients received product at the discretion of their surgeon.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female patients of any age
* Patients who had undergone open or minimal invasive surgical (MIS) procedures requiring the use of a patch to achieve dura repair, hemostasis, or control of leakage of air or other body fluid when pressure, ligature or other conventional procedures had been ineffective or impractical and where use of hemopatch was deemed appropriate by the surgeon according to its IFU in the following organ systems:

1. Hepato-biliary (liver, pancreas, gallbladder)
2. General surgery (in thyroid and other regions)
3. Cardiovascular (heart and vessels)
4. thoracic (lung and mediastinum)
5. Urological (kidney, prostate, and bladder
6. Neurological (dura mater, brain and spinal cord)
* Provision of written informed consent/assent, as applicable, up to 72 hours after the date of surgery

Exclusion Criteria

* Patients with known hypersensitivity to bovine proteins or brilliant blue
* Patients who had intraoperative pulsatile or severe bleeding at the target application site (TAS)
* Patients who had an active infection at the TAS
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Baxter Healthcare Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Innsbruck Universitaetsklinik

Innsbruck, , Austria

Site Status

Fakultní nemocnice u sv. Anny v Brně

Brno, , Czechia

Site Status

Krajská Nemocnice Liberec

Liberec, , Czechia

Site Status

Fakultní Nemocnice Ostrava

Ostrava, , Czechia

Site Status

Thomayerova Nemocnice

Prague, , Czechia

Site Status

Marien-Krankenhaus Bergisch Gladbach

Bergisch Gladbach, , Germany

Site Status

Deutsches Herzzentrum Berlin

Berlin, , Germany

Site Status

ASKLEPIOS Klinik St. Georg

Hamburg, , Germany

Site Status

Universitaetsklinikum Regensburg

Regensburg, , Germany

Site Status

Azienda Ospedaliero-Universitaria Careggi

Florence, , Italy

Site Status

Hospital de Vall d'Hebrón

Barcelona, , Spain

Site Status

Hospital Universitari de Girona Doctor Josep Trueta

Girona, , Spain

Site Status

Hospital General Universitario Gregorio Marañón

Madrid, , Spain

Site Status

Hospital La Paz

Madrid, , Spain

Site Status

Hospital Universitario Virgen del Rocio

Seville, , Spain

Site Status

Countries

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Austria Czechia Germany Italy Spain

References

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Lombardo C, Lopez-Ben S, Boggi U, Gutowski P, Hrbac T, Krska L, Marquez-Rivas J, Russello D, York E, Zacharias M. Hemopatch(R) is effective and safe to use: real-world data from a prospective European registry study. Updates Surg. 2022 Oct;74(5):1521-1531. doi: 10.1007/s13304-022-01353-y. Epub 2022 Aug 20.

Reference Type BACKGROUND
PMID: 35986865 (View on PubMed)

Other Identifiers

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BXU011443

Identifier Type: -

Identifier Source: org_study_id

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