Colonoscopic Adenoma and Advanced Neoplasia Detection Rates According to Age

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

6027 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2016-12-31

Brief Summary

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Current recommendations for colonoscopy screening programs usually involve patients older than 50 years of age. However, little is known about polyp or adenoma detection rates under 50. We compared these detection rates according to age in a large series of patients in common practice.

Methods: All colonoscopies performed in 2016 in our unit were prospectively recorded. We determined adenoma detection rate (ADR), polyp detection rate (PDR), mean number of polyps (MNP), and advanced neoplasia detection rate (ANDR).

Detailed Description

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Patients All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Data collection The following data have been prospectively collected: age, gender, indication for colonoscopy, preparation procedure and quality of the preparation (assessed by the Boston Bowel Preparation Scale; BBPS) \[19-20\], caecal intubation (yes/no), withdrawal time, number and size of polyps and polyp histopathology.

All clinical data were collected during the procedure by a nurse and an endoscopist on a dedicated software. The database was then supplemented by the Clinical Research Associate for histopathological data.

We determined adenoma detection rate (ADR; percentage of colonoscopies with at least one adenoma), polyp detection rate (PDR: percentage of colonoscopies with at least one polyp), mean number of polyps per colonoscopy (MNP), large polyp detection rate (LPDR; percentage of colonoscopies with at least one polyp of 1 cm or more) and advanced neoplasia detection rate (ANDR: percentage of colonoscopies with at least one advanced neoplastic lesion as defined below).

Conditions

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Colonic Polyp Colon Adenoma Colonoscopy Colon Cancer Age

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Colonoscopy

Total colonoscopy : All consecutive patients who were scheduled for colonoscopy were included. Exclusion criteria were: patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All consecutive patients who were scheduled for colonoscopy were included.

Exclusion Criteria

* patients scheduled for partial colonoscopy, interventional colonoscopy (for stent insertion, stenosis dilation).

Minimum Eligible Age

15 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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KARSENTI

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Karsenti, MD

Role: PRINCIPAL_INVESTIGATOR

Pole Digestif Paris-Bercy

Other Identifiers

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2016-ADR according to age

Identifier Type: -

Identifier Source: org_study_id