Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults

NCT ID: NCT03297931

Last Updated: 2025-03-28

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 26 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-07-19
• Study Completion Date: 2024-05-31

Brief Summary

Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer. In fact, 55% of calories consumed by Canadians are ultra processed foods, which are limited in their nutrient profile and only offer empty calories. Subsequently, these foods lead the consumer to eat more and provides little to no feelings of satiety or satiation. the proposed objectives of the current project are to examine the physiological benefit(s) of consuming readily available pulse snacks and compare them to other commonly consumed snack varieties. This work aims to incentivize consumers to seek out pulses as valuable snacking options and highlight the benefit of including these as alternatives to other energy-dense snacks that lack the nutritional composition of pulses.

Detailed Description

Hypothesis of the study: Inclusion of pulses as part of a snack will lower appetite and post-prandial glycemia (PPG) in comparison to commercial, commonly consumed non-pulse snacks.

Overall Objective of the study: To investigate and compare the effects of pulse and non-pulse snacks served as chips and dip on appetite and PPG in healthy adults.

Specific objectives of the study: To test the acute effects of different pulse snacks on: 1) PPG and appetite for three hours, and 2) food intake 1 hour following consumption of snacks.

Conditions

Obesity; Diabetes

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: SINGLE

Study Groups

Commercial corn chips + Onion dip

Corn chips + onion dip

Group Type: ACTIVE_COMPARATOR

Corn Chips + Onion Dip

Intervention Type: DIETARY_SUPPLEMENT

Non-pulse chip + non-pulse dip

Commercial pulse chip + pulse spread

Pinto bean chip + hummus

Group Type: EXPERIMENTAL

Pinto bean chip + hummus

Intervention Type: DIETARY_SUPPLEMENT

Commercial pulse chip + pulse spread

Novel pulse chip + pulse spread

Yellow pea chip + hummus

Group Type: EXPERIMENTAL

Yellow pea chip + hummus

Intervention Type: DIETARY_SUPPLEMENT

Novel pulse chip + pulse spread

Commercial pulse chip + non-pulse spread

Pinto bean chip + onion dip

Group Type: EXPERIMENTAL

Pinto bean chip + onion dip

Intervention Type: DIETARY_SUPPLEMENT

Commercial pulse chip + non-pulse spread

Novel pulse chip + non-pulse spread

Yellow pea chip + onion dip

Group Type: EXPERIMENTAL

Yellow pea chip + onion dip

Intervention Type: DIETARY_SUPPLEMENT

Novel pulse chip + non-pulse spread

Non-pulse chip + pulse spread

Corn chips + hummus

Group Type: EXPERIMENTAL

Corn chips + hummus

Intervention Type: DIETARY_SUPPLEMENT

Non-pulse chip + pulse spread

Interventions

Corn Chips + Onion Dip

Non-pulse chip + non-pulse dip

Intervention Type: DIETARY_SUPPLEMENT

Yellow pea chip + hummus

Novel pulse chip + pulse spread

Intervention Type: DIETARY_SUPPLEMENT

Pinto bean chip + hummus

Commercial pulse chip + pulse spread

Intervention Type: DIETARY_SUPPLEMENT

Pinto bean chip + onion dip

Commercial pulse chip + non-pulse spread

Intervention Type: DIETARY_SUPPLEMENT

Yellow pea chip + onion dip

Novel pulse chip + non-pulse spread

Intervention Type: DIETARY_SUPPLEMENT

Corn chips + hummus

Non-pulse chip + pulse spread

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Age: ≥18 and ≤45 years
• BMI: ≥ 18.5 and ≤ 29.9 kg/m2
• Fasting serum glucose: ≤ 5.6 mmol/L
• Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
• Willing to maintain current dietary supplement use throughout the trial. On test days, subject agrees not to take any dietary supplements until dismissal from the Department of Nutritional Sciences. Failure to comply will result in a rescheduled test visit.
• Willing to abstain from alcohol consumption for 24 h prior to all test visits.
• Willing to avoid vigorous physical activity for 24 h prior to all test visits.
• Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.

Exclusion Criteria

• Fasting blood glucose > 5.6 mmol/L
• Smoking
• Thyroid problems
• Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
• Presence of gastrointestinal disorder or surgeries within the past year.
• Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgement.
• Patients who have undergone bariatric surgery at any point.
• Known to be pregnant or lactating.
• Unwillingness or inability to comply with the experimental procedures
• Known intolerance, sensitivity or allergy to pulses or dairy.
• Extreme dietary habits (ie. Atkins diet, very high protein diets, etc.).
• Uncontrolled hypertension (systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg) as defined by the average blood pressure measured at screening.
• Weight gain or loss of at least 10 lbs in previous three months.
• Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week)
• Restrained Eaters

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Toronto

OTHER

Sponsor Role: lead

Responsible Party

G. Harvey Anderson

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Harvey G Anderson, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Toronto

Locations

University of Toronto

Toronto, Ontario, Canada

Countries

Canada

Other Identifiers

SPG_Snack Study

Identifier Type: -

Identifier Source: org_study_id