The Use of Cyanoacrylate on Palatal Wound

NCT ID: NCT03273010

Last Updated: 2017-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-31

Study Completion Date

2016-12-31

Brief Summary

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The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative complaints.

Detailed Description

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A total of 35 patients were included in the study. In the test group (19 patient), cyanoacrylate was placed over the palatal wounds; conversely, the 16 control group patients were allowed to heal in a conventional way without cyanoacrylate.

Primary bleeding time, presence of secondary bleeding, postoperative pain and completion of epithelization were assessed following free gingival graft operation. As a result, compared to the control group it was determined that the cyanoacrylate tissue adhesive could reduce the postoperative morbidity and improve the wound healing.

Conditions

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Gingival Recession

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Periacryl group

Periacryl, a tissue adhesive, was applied on wound surfaces to achieve haemostasis

Group Type EXPERIMENTAL

Free gingival graft

Intervention Type PROCEDURE

Free gingival graft was harvested from palatal donor site

Cyanoacrylate application

Intervention Type PROCEDURE

Periacyrl was applied on palatal wounds

Control group

Free gingival graft was harvested from palatal region and left to heal without applying periacryl.

Group Type ACTIVE_COMPARATOR

Free gingival graft

Intervention Type PROCEDURE

Free gingival graft was harvested from palatal donor site

Interventions

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Free gingival graft

Free gingival graft was harvested from palatal donor site

Intervention Type PROCEDURE

Cyanoacrylate application

Periacyrl was applied on palatal wounds

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* no systemic diseases
* no coagulation disorders
* no drug intake in the previous 6 months that might effect the periodontal health status
* no pregnancy or lactation
* no smoking habit
* \<1 mm attached gingiva width on one or two lower anterior teeth
* Miller Class I- II- III (Miller 1985) with deep gingival recession (˃ 3mm)

Exclusion Criteria

* Hematologic disorders
* No cooperation
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ordu University

OTHER

Sponsor Role lead

Responsible Party

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Ceren Gökmenoğlu

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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Ordu Uni

Identifier Type: -

Identifier Source: org_study_id

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