The Staircase Phenomenon Implications on Neuromuscular Block Monitoring
NCT ID: NCT03146767
Last Updated: 2017-05-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2013-02-28
2014-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
DOUBLE
Study Groups
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Tetanic Group
A Tetanic stimulation (Tetanus stabilization of baseline) is administered to the monitorized arm before calibrating the neuromuscular block monitor. Then Train-of-four (TOF) stimuli are administered every 20 seconds for 20 minutes.
Tetanus stabilization of baseline
Administering a Tetanic stimulus before baseline stabilization shortens the stabilization period of baseline of a neuromuscular block monitor. This acts on the baseline value
Control Group
Conventional monitor baseline stabilization: Train-of-four stimuli are administered every 20 seconds for 20 minutes
No interventions assigned to this group
Interventions
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Tetanus stabilization of baseline
Administering a Tetanic stimulus before baseline stabilization shortens the stabilization period of baseline of a neuromuscular block monitor. This acts on the baseline value
Eligibility Criteria
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Inclusion Criteria
* Surgery not involving airway performed under general anaesthesia with neuromuscular blocker
Exclusion Criteria
* BMI (Body Mass Idex) \> 35 Kg/m2
* Anticipated difficult airway
* Chronic kidney or hepatic failure
* Neuromuscular disease
* Medication that has known interactions with neuromuscular blockers
* Hemodynamic failure
* Anticipated large blood loss
18 Years
ALL
No
Sponsors
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Hospital Universitario La Fe
OTHER
Responsible Party
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Oscar Diaz-Cambronero
Anesthesiology Consultant
Locations
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Hospital Universitario La Fe
Valencia, , Spain
Countries
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Other Identifiers
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MAZ0816
Identifier Type: -
Identifier Source: org_study_id
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