Use of Neuromuscular Blocking Agents and Neuromuscular Monitoring in 7 Danish Teaching Hospitals

NCT ID: NCT02914119

Last Updated: 2019-09-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30430 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-01

Study Completion Date

2017-06-01

Brief Summary

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Aim: To explore

* the frequency of use of objective neuromuscular monitoring for assessment of depth of neuromuscular blockade in general anaesthesia
* the incidence of residual neuromuscular blockade, and
* the timing of reversal of the neuromuscular blockade at the end of anaesthesia.

We will collect data from 7 Danish anaesthesia departments, using data from the Anaesthesia Information Management System (AIMS).

Detailed Description

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Conditions

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Neuromuscular Blockade

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Eligible patients

Patients ≥15 years of age who received general anaesthesia with neuromuscular blockade in the last 18 months up until the time of data collection.

Patients, who are eligible more than once, i.e. undergoing general anaesthesia on more than one occasion, will be included in the analyses as a case for every general anaesthetic received.

Rocuronium

Intervention Type DRUG

Succinylcholine

Intervention Type DRUG

Cisatracurium

Intervention Type DRUG

Mivacurium

Intervention Type DRUG

Objective neuromuscular monitoring (acceleromyography)

Intervention Type DEVICE

Sugammadex

Intervention Type DRUG

Neostigmine

Intervention Type DRUG

Interventions

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Rocuronium

Intervention Type DRUG

Succinylcholine

Intervention Type DRUG

Cisatracurium

Intervention Type DRUG

Mivacurium

Intervention Type DRUG

Objective neuromuscular monitoring (acceleromyography)

Intervention Type DEVICE

Sugammadex

Intervention Type DRUG

Neostigmine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Patients who received general anaesthesia with neuromuscular blockade in one of the 7 hospitals providing data for the study in the last 18 months up until the time of data collection
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Merck Sharp & Dohme LLC

INDUSTRY

Sponsor Role collaborator

Jakob Louis Thomsen

OTHER

Sponsor Role lead

Responsible Party

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Jakob Louis Thomsen

MD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jakob L Thomsen, MD

Role: PRINCIPAL_INVESTIGATOR

Sponsor principal investigator

Locations

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Herlev Hospital

Herlev, , Denmark

Site Status

Countries

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Denmark

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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JLT-NM4

Identifier Type: -

Identifier Source: org_study_id

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