Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Methods
NCT ID: NCT03095378
Last Updated: 2017-03-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
14 participants
INTERVENTIONAL
2014-03-10
2017-03-10
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Adjunctive Therapies
NCT03462368
Root Biomodification With Citric Acid and Tetracycline Improves the Outcomes of Root Coverage
NCT02259543
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
NCT03207984
Analysis of Root Coverage Stability.
NCT05439382
Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions
NCT02774967
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Control
Root treatment with scaling and root planing.
Control
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with scaling and root planing
Citric acid plus tetracycline
Root treatment with 50% citric acid plus 10% tetracycline, pH1, passive application for 90s.
citric acid plus tetracycline
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with citric acid plus tetracycline
Antimicrobial photodynamic therapy
Antimicrobial photodynamic therapy with toluidine blue O (100ug/ml - 60s pre-irradiation - pH4) and red laser (660nm, 30 milliwatts, 45 joules per square centimeter, sweeping mode, 90s)
antimicrobial photodynamic therapy
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with antimicrobial photodynamic therapy
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Control
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with scaling and root planing
citric acid plus tetracycline
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with citric acid plus tetracycline
antimicrobial photodynamic therapy
Periodontal plastic surgery aiming root coverage by palatal connective tissue graft. Root treatment with antimicrobial photodynamic therapy
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Indication of root coverage by dentin hypersensitivity or esthetic
Exclusion Criteria
* Pregnancy
* Systemic medication use that could impair wound healing or surgery procedure
* Systemic diseases as diabetes, uncontrolled hypertension, coagulation diseases, kidney diseases.
20 Years
50 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Sao Paulo
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Carla Andreotti Damante
Associate professor
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Bauru School of Dentistry
Bauru, São Paulo, Brazil
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Damante CA, Ducati P, Ferreira R, Salmeron S, Zangrando MSR, de Rezende MLR, Sant'Ana ACP, Greghi SLA, Magalhaes AC. In vitro evaluation of adhesion/proliferation of human gingival fibroblasts on demineralized root surfaces by toluidine blue O in antimicrobial photodynamic therapy. Photodiagnosis Photodyn Ther. 2016 Mar;13:303-307. doi: 10.1016/j.pdpdt.2015.08.009. Epub 2015 Sep 7.
Karam PS, Sant'Ana AC, de Rezende ML, Greghi SL, Damante CA, Zangrando MS. Root surface modifiers and subepithelial connective tissue graft for treatment of gingival recessions: a systematic review. J Periodontal Res. 2016 Apr;51(2):175-85. doi: 10.1111/jre.12296. Epub 2015 Jun 11.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
BauruSchoolDentistryPDT
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.