Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-01

Study Completion Date

2019-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodontal and mucogingival surgery as a substitute for CTG and has achieved similar results. The CM has the advantage of no need of a second surgical area and availability overcoming the limitations of donor site in autograft.

The aim of this study is to investigate the use of Mucoderm® in root coverage procedures combined with extended coronally positioned flap (ECAF), test group (TG), in comparison to the connective tissue graft associated with the ECAF, control group (CG).

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Connective Tissue Graft Versus Mucograft Collagen Matrix for Coverage of Multiple Gingival Recession Defects

NCT01440426

Gingival Recession

COMPLETED PHASE4

Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions

NCT03207984

Gingival Recession, Generalized

COMPLETED NA

Mucoderm® Versus CTG in the Treatment of Multiple Gingival Recessions Associated With Non-carious Cervical Lesion.

NCT03594513

Gingival Recession Tooth Abrasion

UNKNOWN NA

Two Different Surgical Techniques for the Treatment of Multiple Gingival Recessions With Porcine Collagen Matrix

NCT03619096

Gingival Recession Xenograft Model Gingival Recession, Generalized

UNKNOWN NA

Comparation Between Two Surgical Techniques With Acellular Dermal Matrix in Treatment of Gingival Recessions

NCT02774967

Gingival Recession Gingival Diseases Mouth Diseases +3 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Gingival Recession

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Split-mouth clinical trial

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

The clinical parameters were screened by one single examiner that was not aware of the procedures

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Test Group

Active comparator: gingival recession

the aim of this study is to compare if the collagen matrix graft is as efficient as a substitute for the connective graft used in root coverage of gingival recessions

Group Type ACTIVE_COMPARATOR

Root coverage with collagen matrix graft

Intervention Type PROCEDURE

at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.

Basic periodontal treatment

Intervention Type OTHER

profilaxis, coronary polishing and scaling and root planning

Control Group

the aim of this study is to compare if the collagen matrix graft is as efficient as a substitute for the connective graft used in root coverage of gingival recessions. The control group was treated with the same technique as the collagen matrix graft.

Group Type PLACEBO_COMPARATOR

Root coverage with subepithelial connective tissue graft

Intervention Type PROCEDURE

at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.

Basic periodontal treatment

Intervention Type OTHER

profilaxis, coronary polishing and scaling and root planning

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Root coverage with collagen matrix graft

at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.

Intervention Type PROCEDURE

Root coverage with subepithelial connective tissue graft

at one side, the root coverage have been done with a extended flap technique and collagen matrix graft. At the other side, the same technique was performed with connective graft.

Intervention Type PROCEDURE

Basic periodontal treatment

profilaxis, coronary polishing and scaling and root planning

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* CEJ without significant damage;
* localized bilateral RT1 gingival recession ≥3 mm in the same arch

Exclusion Criteria

* previous periodontal surgical treatment on the involved sites;
* smokers
* pregnants or lactating
* compromised systemic health and contraindications for periodontal surgery

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes