Effect of Multisensory Stimulation on Upper Extremity Motor Recovery in Stroke Patient: a Preliminary Testing

NCT ID: NCT03094377

Last Updated: 2017-03-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 12 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-03-01
• Study Completion Date: 2015-12-31

Brief Summary

Despite the advances in stroke rehabilitation, post-stroke upper extremity impairment is still a major challenge. Increasing evidence can be found supporting stimulation of the afferent receptor enhances neuroplasticity in the brain. Studies have suggested multisensory stimulation could promote motor learning by re-establishing the disrupted sensorimotor loop due to stroke and enhance neuroplasticity.

The objective of the study was to examine the effect of multisensory stimulation on upper-extremity motor recovery and self-care function in stroke patients.

Detailed Description

Stroke patients referred to occupational therapy division of geriatric day hospital will be recruited and randomly assigned to a multisensory therapy group or a conventional training group. The Multisensory therapy group received 12 weeks (two sessions/ week; 90 minutes/session) training. Each session began with 15 minutes of sensory stimulation (cold and vibration), 45 minutes of motor training and 30 minutes of self-care training. The conventional training group included 12 weeks (two sessions/ week; 90 minutes/session) training. Each session included 60 minutes of upper extremity motor practice and 30 minutes of self-care training.

Outcome measures included: Brunnstrom's stage, Fugl-Meyer Assessment Scale and Functional Test for the Hemiplegic Upper Extremity were used for upper limb motor control and function; and Manual muscle testing was used for muscle strength. The modified Barthel Index was used for self-care performance

Conditions

Stroke

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Multisensory therapy group

The Multisensory therapy (MT) group received a 12-weeks (two sessions/ week; 90 minutes/session) training conducted by an occupational therapist. Each session began with 15 minutes of sensory stimulation (cold and vibration), 45 minutes of motor training and 30 minutes of self-care training.

Group Type: EXPERIMENTAL

Multisensory therapy

Intervention Type: OTHER

Sensory stimulation, motor training and ADL training

Conventional training group

The conventional training (CT) group included 12 weeks (two sessions/ week; 90 minutes/session) training conducted by an occupational therapist. Each session included 60 minutes of upper extremity motor practice (same as in MT group) and 30 minutes of self-care training (same as in MT group).

Group Type: ACTIVE_COMPARATOR

Conventional training

Intervention Type: OTHER

Motor training and ADL training

Interventions

Multisensory therapy

Sensory stimulation, motor training and ADL training

Intervention Type: OTHER

Conventional training

Motor training and ADL training

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• First-time ischemic or hemorrhagic stroke;
• Stroke onset > 4 weeks and < 6 months
• Single lesion
• Upper extremity motor deficit
• No severe cognitive impairment and able to follow verbal instructions.

Exclusion Criteria

• Skin conditions/ injuries over the stimulation application areas
• Contraindication for cold or vibration application
• Speech disorder or global aphasia
• Musculoskeletal or cardiac disorders
• Other neurological conditions
• History of diabetes or sensory impairment attributable to peripheral vascular disease or neuropathy

• Minimum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tung Wah College

OTHER

Sponsor Role: lead

Responsible Party

Ray KF Li

Principal Investigator, Adjunct Lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Ray Li, Master

Role: PRINCIPAL_INVESTIGATOR

Occupational Therapist

Locations

Wong Tai Sin Hospital

Wong Tai Sin, , Hong Kong

Countries

Hong Kong

Other Identifiers

U1111-1193-6547

Identifier Type: -

Identifier Source: org_study_id